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Conference Paper: Effects of chronic ocular hypertension and hypotensive drug treatment on ocular physiology and biotransport using dynamic gadolinium-enhanced MRI

TitleEffects of chronic ocular hypertension and hypotensive drug treatment on ocular physiology and biotransport using dynamic gadolinium-enhanced MRI
Authors
Ho, LCConner, IPKi, SGWu, EXDo, CWWollstein, GSchuman, JSChan, KC
Issue Date2014
PublisherISMRM-ESMRMB 2014.
Citation
The 2014 joint ISMRM-ESMRMB Annual Meeting, Milano, Italy, 10-16 May 2014. How to Cite?
AbstractBalanced aqueous humor flow dynamics is crucial to maintain healthy ocular physiology. Imbalanced aqueous humor flow dynamics would lead to altered intraocular pressure and retinal damage or visual loss in glaucoma disease. To date, the relationships between eye pressure, aqueous humor flow and glaucoma are not fully evaluated. Gd-enhanced MRI may non-invasively visualize flow dynamics of aqueous humor. In this study, dynamic Gd-enhanced MRI was employed to evaluate in vivo the ocular physiology and biotransport in a rat model of microbead-induced ocular hypertension and in healthy, normotensive rats after topical applications of 3 different ophthalmic hypotensive eye drops.
DescriptionElectronic Poster Session - Perfusion: Perfusion & Permeability: no. 4589
Persistent Identifierhttp://hdl.handle.net/10722/204160

 

DC FieldValueLanguage
dc.contributor.authorHo, LCen_US
dc.contributor.authorConner, IPen_US
dc.contributor.authorKi, SGen_US
dc.contributor.authorWu, EXen_US
dc.contributor.authorDo, CWen_US
dc.contributor.authorWollstein, Gen_US
dc.contributor.authorSchuman, JSen_US
dc.contributor.authorChan, KCen_US
dc.date.accessioned2014-09-19T20:07:30Z-
dc.date.available2014-09-19T20:07:30Z-
dc.date.issued2014en_US
dc.identifier.citationThe 2014 joint ISMRM-ESMRMB Annual Meeting, Milano, Italy, 10-16 May 2014.en_US
dc.identifier.urihttp://hdl.handle.net/10722/204160-
dc.descriptionElectronic Poster Session - Perfusion: Perfusion & Permeability: no. 4589-
dc.description.abstractBalanced aqueous humor flow dynamics is crucial to maintain healthy ocular physiology. Imbalanced aqueous humor flow dynamics would lead to altered intraocular pressure and retinal damage or visual loss in glaucoma disease. To date, the relationships between eye pressure, aqueous humor flow and glaucoma are not fully evaluated. Gd-enhanced MRI may non-invasively visualize flow dynamics of aqueous humor. In this study, dynamic Gd-enhanced MRI was employed to evaluate in vivo the ocular physiology and biotransport in a rat model of microbead-induced ocular hypertension and in healthy, normotensive rats after topical applications of 3 different ophthalmic hypotensive eye drops.-
dc.languageengen_US
dc.publisherISMRM-ESMRMB 2014.-
dc.relation.ispartofISMRM-ESMRMB Annual Meeting 2014en_US
dc.titleEffects of chronic ocular hypertension and hypotensive drug treatment on ocular physiology and biotransport using dynamic gadolinium-enhanced MRIen_US
dc.typeConference_Paperen_US
dc.identifier.emailWu, EX: ewu1@hkucc.hku.hken_US
dc.identifier.authorityWu, EX=rp00193en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros240638en_US
dc.publisher.placeItalyen_US

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