File Download
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.2217/fon.15.40
- Scopus: eid_2-s2.0-84930518040
- Find via
Supplementary
-
Citations:
- Scopus: 0
- Appears in Collections:
Conference Paper: Primary breast cancer in older Chinese women as compared to their younger counterparts
Title | Primary breast cancer in older Chinese women as compared to their younger counterparts |
---|---|
Authors | |
Keywords | Medical sciences Oncology |
Issue Date | 2015 |
Publisher | Future Medicine Ltd. The Journal's web site is located at http://www.futuremedicine.com/loi/fon |
Citation | The 3rd Symposium on Primary Breast Cancer in Older Women, Nottingham, UK., 6 March 2015. In Future Oncology, 2015, v. 11 n. 4 suppl., p. 18, abstract P8 How to Cite? |
Abstract | Background: This study aims to investigate the treatment, tumor biology and survival of breast cancer in elderly Chinese patients. A comparison was made with their younger counterparts. Methods: A retrospective study of patients with breast cancer who have undergone surgery in a university hospital from January 2001 to December 2009 was performed. Treatment options, tumor characteristics
and survival of patients aged 70 and above were compared with those aged below 70. Results: 2826 Chinese patients with breast cancer underwent surgery during the study period. 394 patients (14%) were aged 70 and above, and 2432 patients (86%) were aged below 70. More elderly patients had astectomy than breast conservation (p < 0.0005). Less elderly patients received chemotherapy and radiotherapy (p < 0.0005). The use of hormonal therapy was similar between the two groups. Breast cancer in older women were of better histological grading (P < 0.0005), more estrogen receptor positive (p = 0.03) and less HER-2 oncogene overexpression (p = 0.016). The overall median survival for elderly patients was 5.27 years, which is worse than their younger counterparts (6.48 years; p < 0.0005), whereas the breast cancer specific survival were comparable between these two age groups. Discussion: Older Chinese women with breast cancer received less aggressive treatment. Despite this, the breast cancer specific survival in this older age group women was similar to that of their younger counterparts. This may be attributed to the better tumor prognostic indexes. The overall survival in elderly patients was worse, which may be explained by the presence of other non-cancer related causes of death. |
Description | Conference Theme: Personalising the management of primary breast cancer in older women Abstract & poster presentation This free journal suppl. entitled: Third Symposium on Primary Breast Cancer in Older Women |
Persistent Identifier | http://hdl.handle.net/10722/218993 |
ISSN | 2023 Impact Factor: 3.0 2023 SCImago Journal Rankings: 1.029 |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Suen, DTK | - |
dc.contributor.author | Ma, KK | - |
dc.contributor.author | Kwong, A | - |
dc.date.accessioned | 2015-09-18T07:03:17Z | - |
dc.date.available | 2015-09-18T07:03:17Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | The 3rd Symposium on Primary Breast Cancer in Older Women, Nottingham, UK., 6 March 2015. In Future Oncology, 2015, v. 11 n. 4 suppl., p. 18, abstract P8 | - |
dc.identifier.issn | 1479-6694 | - |
dc.identifier.uri | http://hdl.handle.net/10722/218993 | - |
dc.description | Conference Theme: Personalising the management of primary breast cancer in older women | - |
dc.description | Abstract & poster presentation | - |
dc.description | This free journal suppl. entitled: Third Symposium on Primary Breast Cancer in Older Women | - |
dc.description.abstract | Background: This study aims to investigate the treatment, tumor biology and survival of breast cancer in elderly Chinese patients. A comparison was made with their younger counterparts. Methods: A retrospective study of patients with breast cancer who have undergone surgery in a university hospital from January 2001 to December 2009 was performed. Treatment options, tumor characteristics and survival of patients aged 70 and above were compared with those aged below 70. Results: 2826 Chinese patients with breast cancer underwent surgery during the study period. 394 patients (14%) were aged 70 and above, and 2432 patients (86%) were aged below 70. More elderly patients had astectomy than breast conservation (p < 0.0005). Less elderly patients received chemotherapy and radiotherapy (p < 0.0005). The use of hormonal therapy was similar between the two groups. Breast cancer in older women were of better histological grading (P < 0.0005), more estrogen receptor positive (p = 0.03) and less HER-2 oncogene overexpression (p = 0.016). The overall median survival for elderly patients was 5.27 years, which is worse than their younger counterparts (6.48 years; p < 0.0005), whereas the breast cancer specific survival were comparable between these two age groups. Discussion: Older Chinese women with breast cancer received less aggressive treatment. Despite this, the breast cancer specific survival in this older age group women was similar to that of their younger counterparts. This may be attributed to the better tumor prognostic indexes. The overall survival in elderly patients was worse, which may be explained by the presence of other non-cancer related causes of death. | - |
dc.language | eng | - |
dc.publisher | Future Medicine Ltd. The Journal's web site is located at http://www.futuremedicine.com/loi/fon | - |
dc.relation.ispartof | Future Oncology | - |
dc.rights | Manuscripts that have been submitted for publication and entry into peer review | - |
dc.subject | Medical sciences | - |
dc.subject | Oncology | - |
dc.title | Primary breast cancer in older Chinese women as compared to their younger counterparts | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Suen, DTK: suentkd@hku.hk | - |
dc.identifier.email | Ma, KK: drkkma@hku.hk | - |
dc.identifier.email | Kwong, A: avakwong@hkucc.hku.hk | - |
dc.identifier.authority | Kwong, A=rp01734 | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.2217/fon.15.40 | - |
dc.identifier.scopus | eid_2-s2.0-84930518040 | - |
dc.identifier.hkuros | 251987 | - |
dc.identifier.volume | 11 | - |
dc.identifier.issue | 4 suppl. | - |
dc.identifier.spage | 18, abstract P8 | - |
dc.identifier.epage | 18, abstract P8 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 1479-6694 | - |