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Conference Paper: High pulse rate acoustic stimulation reduces fMRI responses in the auditory thalamus and cortex of chronic noise exposed rats

TitleHigh pulse rate acoustic stimulation reduces fMRI responses in the auditory thalamus and cortex of chronic noise exposed rats
Authors
Issue Date2015
Citation
The 23rd Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM) and SMRT 24th Annual Meeting, Toronto, ON., Canada, 30 May-5 June 2015, poster no. 3908 How to Cite?
AbstractLong-term acoustic noise exposure at moderate sound pressure levels (SPLs) (within occupational limits) can be detrimental to speech intelligibility by altering its spectrotemporal representation in the auditory system. To test this, we performed fMRI on adult rats exposed to 65dB SPL noise for two months. The results show noise exposure reduces fMRI signals in the auditory thalamus and cortex. The reduction is greater during 10 than 5Hz pulse rate acoustic stimulation. These findings are important for speech processing, which depends on accurate processing of sounds with a wide spectrum of rates.
DescriptionElectronic Poster Session: Functional MRI (Neuro) - Preclinical fMRI: no. 3908
Persistent Identifierhttp://hdl.handle.net/10722/220313

 

DC FieldValueLanguage
dc.contributor.authorLau, C-
dc.contributor.authorZhang, JW-
dc.contributor.authorWu, EX-
dc.date.accessioned2015-10-16T06:37:27Z-
dc.date.available2015-10-16T06:37:27Z-
dc.date.issued2015-
dc.identifier.citationThe 23rd Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM) and SMRT 24th Annual Meeting, Toronto, ON., Canada, 30 May-5 June 2015, poster no. 3908-
dc.identifier.urihttp://hdl.handle.net/10722/220313-
dc.descriptionElectronic Poster Session: Functional MRI (Neuro) - Preclinical fMRI: no. 3908-
dc.description.abstractLong-term acoustic noise exposure at moderate sound pressure levels (SPLs) (within occupational limits) can be detrimental to speech intelligibility by altering its spectrotemporal representation in the auditory system. To test this, we performed fMRI on adult rats exposed to 65dB SPL noise for two months. The results show noise exposure reduces fMRI signals in the auditory thalamus and cortex. The reduction is greater during 10 than 5Hz pulse rate acoustic stimulation. These findings are important for speech processing, which depends on accurate processing of sounds with a wide spectrum of rates.-
dc.languageeng-
dc.relation.ispartofISMRM 23rd Annual Meeting & Exhibition cum SMRT 24th Annual Meeting Proceedings-
dc.titleHigh pulse rate acoustic stimulation reduces fMRI responses in the auditory thalamus and cortex of chronic noise exposed rats-
dc.typeConference_Paper-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.identifier.authorityWu, EX=rp00193-
dc.identifier.hkuros255299-

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