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Conference Paper: Auditory and visual cortices differentially modulate auditory responses in the midbrain
Title | Auditory and visual cortices differentially modulate auditory responses in the midbrain |
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Authors | |
Issue Date | 2015 |
Citation | The 23rd Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM) and SMRT 24th Annual Meeting, Toronto, ON., Canada, 30 May-5 June 2015, poster no. 3907 How to Cite? |
Abstract | The cortex is commonly thought of as the site at which ascending projections from all sensory modalities are integrated, yet cortical feedback to subcortical nuclei modulates early information processing. Here, we demonstrate that descending inputs from both auditory and visual cortex are integrated in the auditory midbrain. Using BOLD fMRI to measure sound-evoked responses throughout the auditory midbrain, we show that auditory cortical input normally suppresses the gain of midbrain response, while visual cortical input increases the gain. Our results demonstrate the large-scale influence of cortical projections from more than one sensory modality, demonstrating that while ascending integration occurs in cortex, descending integration occurs in the brainstem. |
Description | Electronic Poster Session: Functional MRI (Neuro) - Preclinical fMRI: no. 3907 |
Persistent Identifier | http://hdl.handle.net/10722/220319 |
DC Field | Value | Language |
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dc.contributor.author | Gao, PP | - |
dc.contributor.author | Zhang, JW | - |
dc.contributor.author | Fan, SJ | - |
dc.contributor.author | Sanes, DH | - |
dc.contributor.author | Wu, EX | - |
dc.date.accessioned | 2015-10-16T06:37:50Z | - |
dc.date.available | 2015-10-16T06:37:50Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | The 23rd Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM) and SMRT 24th Annual Meeting, Toronto, ON., Canada, 30 May-5 June 2015, poster no. 3907 | - |
dc.identifier.uri | http://hdl.handle.net/10722/220319 | - |
dc.description | Electronic Poster Session: Functional MRI (Neuro) - Preclinical fMRI: no. 3907 | - |
dc.description.abstract | The cortex is commonly thought of as the site at which ascending projections from all sensory modalities are integrated, yet cortical feedback to subcortical nuclei modulates early information processing. Here, we demonstrate that descending inputs from both auditory and visual cortex are integrated in the auditory midbrain. Using BOLD fMRI to measure sound-evoked responses throughout the auditory midbrain, we show that auditory cortical input normally suppresses the gain of midbrain response, while visual cortical input increases the gain. Our results demonstrate the large-scale influence of cortical projections from more than one sensory modality, demonstrating that while ascending integration occurs in cortex, descending integration occurs in the brainstem. | - |
dc.language | eng | - |
dc.relation.ispartof | ISMRM 23rd Annual Meeting & Exhibition cum SMRT 24th Annual Meeting Proceedings | - |
dc.title | Auditory and visual cortices differentially modulate auditory responses in the midbrain | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Wu, EX: ewu@eee.hku.hk | - |
dc.identifier.authority | Wu, EX=rp00193 | - |
dc.identifier.hkuros | 255321 | - |