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Conference Paper: Mapping silver-binding proteins in staphylococcus aureus by liquid chromatography combined with gel electrophoresis and inductively coupled plasma mass spectrometry
Title | Mapping silver-binding proteins in staphylococcus aureus by liquid chromatography combined with gel electrophoresis and inductively coupled plasma mass spectrometry |
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Authors | |
Keywords | Metallomics Silver Antimicrobial Protein targets GE-ICP-MS |
Issue Date | 2015 |
Citation | The 5th Asian Conference on Coordination Chemistry (ACCC-5), Hong Kong,12-16 July 2015. In Abstracts Book, 2015, p. 153 How to Cite? |
Abstract | Metals play a crucial role in life processes and metallodrugs have been extensively used for therapeutic and diagnosis purposes.1To understand mode of action of metallodrugs, reduce toxicity, and overcome resistance as well as to design new drugs more rationally, exploring their protein targets is imperative. Silver has been used as an antimicrobial since antiquity, yet its targetsand mechanism of action remain obscure.1LA-ICP-MS and SXRF are the main metallomic approaches utilized to determine metal-binding proteins, whereas the low sensitivity ascribed to the laser system ... |
Description | Poster Presentation: P-63 |
Persistent Identifier | http://hdl.handle.net/10722/220666 |
DC Field | Value | Language |
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dc.contributor.author | Wang, H | - |
dc.contributor.author | Wang, Y | - |
dc.contributor.author | Hu, L | - |
dc.contributor.author | Sun, H | - |
dc.date.accessioned | 2015-10-16T06:48:55Z | - |
dc.date.available | 2015-10-16T06:48:55Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | The 5th Asian Conference on Coordination Chemistry (ACCC-5), Hong Kong,12-16 July 2015. In Abstracts Book, 2015, p. 153 | - |
dc.identifier.uri | http://hdl.handle.net/10722/220666 | - |
dc.description | Poster Presentation: P-63 | - |
dc.description.abstract | Metals play a crucial role in life processes and metallodrugs have been extensively used for therapeutic and diagnosis purposes.1To understand mode of action of metallodrugs, reduce toxicity, and overcome resistance as well as to design new drugs more rationally, exploring their protein targets is imperative. Silver has been used as an antimicrobial since antiquity, yet its targetsand mechanism of action remain obscure.1LA-ICP-MS and SXRF are the main metallomic approaches utilized to determine metal-binding proteins, whereas the low sensitivity ascribed to the laser system ... | - |
dc.language | eng | - |
dc.relation.ispartof | Asian Conference on Coordination Chemistry, ACCC-5 | - |
dc.subject | Metallomics | - |
dc.subject | Silver | - |
dc.subject | Antimicrobial | - |
dc.subject | Protein targets | - |
dc.subject | GE-ICP-MS | - |
dc.title | Mapping silver-binding proteins in staphylococcus aureus by liquid chromatography combined with gel electrophoresis and inductively coupled plasma mass spectrometry | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Hu, L: liganghu@hku.hk | - |
dc.identifier.email | Sun, H: hsun@hku.hk | - |
dc.identifier.authority | Sun, H=rp00777 | - |
dc.description.nature | postprint | - |
dc.identifier.hkuros | 255559 | - |
dc.identifier.hkuros | 268495 | - |
dc.identifier.spage | 153 | - |
dc.identifier.epage | 153 | - |