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- Publisher Website: 10.1007/s11136-016-1254-1
- Scopus: eid_2-s2.0-84959114875
- PMID: 26908258
- WOS: WOS:000382991000025
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Article: The internal and external responsiveness of Functional Assessment of Cancer Therapy-Prostate (FACT-P) and Short Form-12 Health Survey version 2 (SF-12 v2) in patients with prostate cancer
Title | The internal and external responsiveness of Functional Assessment of Cancer Therapy-Prostate (FACT-P) and Short Form-12 Health Survey version 2 (SF-12 v2) in patients with prostate cancer |
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Authors | |
Keywords | FACT-P Chinese SF-12 Health-related quality of life Responsiveness Prostate cancer Instrument |
Issue Date | 2016 |
Publisher | Springer Verlag Dordrecht. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0962-9343 |
Citation | Quality of Life Research, 2016, v. 25 n. 9, p. 2379-2393 How to Cite? |
Abstract | Purpose: To examine the responsiveness of Functional Assessment of Cancer Therapy-Prostate (FACT-P) and Short Form-12 Health Survey version 2 (SF-12 v2) in prostate cancer patients because there is a lack of evidence to support their responsiveness in prostate cancer patients. Methods: One hundred sixty-eight subjects with prostate cancer were surveyed at baseline and at 6 months using the SF-12 v2 and FACT-P version 4. Internal responsiveness was assessed using paired t test and generalized estimating equation. External responsiveness was evaluated using receiver operating characteristic curve analysis. Results: The internal responsiveness of the FACT-P and SF-12 v2 to detect positive change was satisfactory. The FACT-P and SF-12 v2 could not detect negative change. The FACT-P and the SF-12 v2 performed the best in distinguishing between improved general health and worsened general health. The FACT-P performed better in distinguishing between unchanged general health and worsened general health. The SF-12 v2 performed better in distinguishing between unchanged general health and improved general health. Conclusions: Positive change detected by these measures should be interpreted with caution as they might be too responsive to detect “noise,” which is not clinically significant. The ability of the FACT-P and the SF-12 v2 to detect negative change was disappointing. The internal and external responsiveness of the social well-being of the FACT-P cannot be supported, suggesting that it is not suitable to longitudinally monitor the social component of HRQOL in prostate cancer patients. The study suggested that generic and disease-specific measures should be used together to complement each other. |
Persistent Identifier | http://hdl.handle.net/10722/223856 |
ISSN | 2023 Impact Factor: 3.3 2023 SCImago Journal Rankings: 1.299 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Choi, EPH | - |
dc.contributor.author | Wong, CKH | - |
dc.contributor.author | Wan, EYF | - |
dc.contributor.author | Tsu, HLJ | - |
dc.contributor.author | Chin, WY | - |
dc.contributor.author | Kung, K | - |
dc.contributor.author | Yiu, MK | - |
dc.date.accessioned | 2016-03-18T02:30:00Z | - |
dc.date.available | 2016-03-18T02:30:00Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | Quality of Life Research, 2016, v. 25 n. 9, p. 2379-2393 | - |
dc.identifier.issn | 0962-9343 | - |
dc.identifier.uri | http://hdl.handle.net/10722/223856 | - |
dc.description.abstract | Purpose: To examine the responsiveness of Functional Assessment of Cancer Therapy-Prostate (FACT-P) and Short Form-12 Health Survey version 2 (SF-12 v2) in prostate cancer patients because there is a lack of evidence to support their responsiveness in prostate cancer patients. Methods: One hundred sixty-eight subjects with prostate cancer were surveyed at baseline and at 6 months using the SF-12 v2 and FACT-P version 4. Internal responsiveness was assessed using paired t test and generalized estimating equation. External responsiveness was evaluated using receiver operating characteristic curve analysis. Results: The internal responsiveness of the FACT-P and SF-12 v2 to detect positive change was satisfactory. The FACT-P and SF-12 v2 could not detect negative change. The FACT-P and the SF-12 v2 performed the best in distinguishing between improved general health and worsened general health. The FACT-P performed better in distinguishing between unchanged general health and worsened general health. The SF-12 v2 performed better in distinguishing between unchanged general health and improved general health. Conclusions: Positive change detected by these measures should be interpreted with caution as they might be too responsive to detect “noise,” which is not clinically significant. The ability of the FACT-P and the SF-12 v2 to detect negative change was disappointing. The internal and external responsiveness of the social well-being of the FACT-P cannot be supported, suggesting that it is not suitable to longitudinally monitor the social component of HRQOL in prostate cancer patients. The study suggested that generic and disease-specific measures should be used together to complement each other. | - |
dc.language | eng | - |
dc.publisher | Springer Verlag Dordrecht. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0962-9343 | - |
dc.relation.ispartof | Quality of Life Research | - |
dc.rights | The final publication is available at Springer via http://dx.doi.org/10.1007/s11136-016-1254-1 | - |
dc.subject | FACT-P | - |
dc.subject | Chinese | - |
dc.subject | SF-12 | - |
dc.subject | Health-related quality of life | - |
dc.subject | Responsiveness | - |
dc.subject | Prostate cancer | - |
dc.subject | Instrument | - |
dc.title | The internal and external responsiveness of Functional Assessment of Cancer Therapy-Prostate (FACT-P) and Short Form-12 Health Survey version 2 (SF-12 v2) in patients with prostate cancer | - |
dc.type | Article | - |
dc.identifier.email | Choi, EPH: ephchoi@hku.hk | - |
dc.identifier.email | Wong, CKH: carlosho@hku.hk | - |
dc.identifier.email | Wan, EYF: yfwan@hku.hk | - |
dc.identifier.email | Tsu, HLJ: jamestsu@hku.hk | - |
dc.identifier.email | Chin, WY: chinwy@hku.hk | - |
dc.identifier.email | Kung, K: kkung@hku.hk | - |
dc.identifier.email | Yiu, MK: pmkyiu@hku.hk | - |
dc.identifier.authority | Wong, CKH=rp01931 | - |
dc.identifier.authority | Chin, WY=rp00290 | - |
dc.identifier.authority | Kung, K=rp01974 | - |
dc.description.nature | postprint | - |
dc.identifier.doi | 10.1007/s11136-016-1254-1 | - |
dc.identifier.pmid | 26908258 | - |
dc.identifier.scopus | eid_2-s2.0-84959114875 | - |
dc.identifier.hkuros | 257160 | - |
dc.identifier.volume | 25 | - |
dc.identifier.issue | 9 | - |
dc.identifier.spage | 2379 | - |
dc.identifier.epage | 2393 | - |
dc.identifier.isi | WOS:000382991000025 | - |
dc.publisher.place | Netherlands | - |
dc.identifier.issnl | 0962-9343 | - |