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- PMID: 28773535
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Article: Inhibition of Cariogenic Plaque Formation on Root Surface with Polydopamine-Induced-Polyethylene Glycol Coating
Title | Inhibition of Cariogenic Plaque Formation on Root Surface with Polydopamine-Induced-Polyethylene Glycol Coating |
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Authors | |
Keywords | Biofouling Dentine Polydopamine Polyethylene Root caries |
Issue Date | 2016 |
Citation | Materials, 2016, v. 9 n. 6, article no.. 414 How to Cite? |
Abstract | Root caries prevention has been a challenge for clinicians due to its special anatomical location, which favors the accumulation of dental plaque. Researchers are looking for anti-biofouling material to inhibit bacterial growth on exposed root surfaces. This study aimed to develop polydopamine-induced-polyethylene glycol (PEG) and to study its anti-biofouling effect against a multi-species cariogenic biofilm on the root dentine surface. Hydroxyapatite disks and human dentine blocks were divided into four groups for experiments. They received polydopamine-induced-PEG, PEG, polydopamine, or water application. Contact angle, quartz crystal microbalance, and Fourier transform infrared spectroscopy were used to study the wetting property, surface affinity, and an infrared spectrum; the results indicated that PEG was induced by polydopamine onto a hydroxyapatite disk. Salivary mucin absorption on hydroxyapatite disks with polydopamine-induced-PEG was confirmed using spectrophotometry. The growth of a multi-species cariogenic biofilm on dentine blocks with polydopamine-induced-PEG was assessed and monitored by colony-forming units, confocal laser scanning microscopy, and scanning electron microscopy. The results showed that dentine with polydopamine-induced-PEG had fewer bacteria than other groups. In conclusion, a novel polydopamine-induced-PEG coating was developed. Its anti-biofouling effect inhibited salivary mucin absorption and cariogenic biofilm formation on dentine surface and thus may be used for the prevention of root dentine caries. |
Persistent Identifier | http://hdl.handle.net/10722/226301 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Mei, L | - |
dc.contributor.author | Li, QL | - |
dc.contributor.author | Chu, CH | - |
dc.date.accessioned | 2016-06-17T07:43:10Z | - |
dc.date.available | 2016-06-17T07:43:10Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | Materials, 2016, v. 9 n. 6, article no.. 414 | - |
dc.identifier.uri | http://hdl.handle.net/10722/226301 | - |
dc.description.abstract | Root caries prevention has been a challenge for clinicians due to its special anatomical location, which favors the accumulation of dental plaque. Researchers are looking for anti-biofouling material to inhibit bacterial growth on exposed root surfaces. This study aimed to develop polydopamine-induced-polyethylene glycol (PEG) and to study its anti-biofouling effect against a multi-species cariogenic biofilm on the root dentine surface. Hydroxyapatite disks and human dentine blocks were divided into four groups for experiments. They received polydopamine-induced-PEG, PEG, polydopamine, or water application. Contact angle, quartz crystal microbalance, and Fourier transform infrared spectroscopy were used to study the wetting property, surface affinity, and an infrared spectrum; the results indicated that PEG was induced by polydopamine onto a hydroxyapatite disk. Salivary mucin absorption on hydroxyapatite disks with polydopamine-induced-PEG was confirmed using spectrophotometry. The growth of a multi-species cariogenic biofilm on dentine blocks with polydopamine-induced-PEG was assessed and monitored by colony-forming units, confocal laser scanning microscopy, and scanning electron microscopy. The results showed that dentine with polydopamine-induced-PEG had fewer bacteria than other groups. In conclusion, a novel polydopamine-induced-PEG coating was developed. Its anti-biofouling effect inhibited salivary mucin absorption and cariogenic biofilm formation on dentine surface and thus may be used for the prevention of root dentine caries. | - |
dc.language | eng | - |
dc.relation.ispartof | Materials | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Biofouling | - |
dc.subject | Dentine | - |
dc.subject | Polydopamine | - |
dc.subject | Polyethylene | - |
dc.subject | Root caries | - |
dc.title | Inhibition of Cariogenic Plaque Formation on Root Surface with Polydopamine-Induced-Polyethylene Glycol Coating | - |
dc.type | Article | - |
dc.identifier.email | Mei, L: mei1123@hku.hk | - |
dc.identifier.email | Chu, CH: chchu@hku.hk | - |
dc.identifier.authority | Mei, L=rp01840 | - |
dc.identifier.authority | Chu, CH=rp00022 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.3390/ma9060414 | - |
dc.identifier.pmid | 28773535 | - |
dc.identifier.pmcid | PMC5456761 | - |
dc.identifier.scopus | eid_2-s2.0-84975770093 | - |
dc.identifier.hkuros | 258480 | - |
dc.identifier.volume | 9 | - |
dc.identifier.spage | article no.. 414 | - |
dc.identifier.epage | article no.. 414 | - |
dc.identifier.eissn | 1996-1944 | - |
dc.identifier.isi | WOS:000378630600013 | - |
dc.identifier.issnl | 1996-1944 | - |