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Conference Paper: Radiation-induced early temporal changes of IVIM-based diffusion and perfusion patterns of bone marrow predict the likelihood of hematological toxicity
| Title | Radiation-induced early temporal changes of IVIM-based diffusion and perfusion patterns of bone marrow predict the likelihood of hematological toxicity |
|---|---|
| Authors | |
| Issue Date | 2016 |
| Citation | The 24th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2016), Singapore, 7-13 May 2016. How to Cite? |
| Abstract | Intravoxel incoherent motion (IVIM) diffusion-weighted MRI offers the unique opportunity to simultaneously study the diffusion and perfusion changes in the bone marrow following whole-pelvis radiotherapy. We prospectively studied twenty-eight patients with cervical cancer who had paired IVIM MRI examinations before and at week-4 of treatment. We observed a distinctive positive trend of D (true diffusion coefficient) in patients who suffered hematological toxicity (HT), whilst D remained relatively stable in patients who did not suffer HT. In addition, f (perfusion fraction) increased following treatment, but this pattern was not unique to patients who suffered HT. |
| Description | Electronic Poster Session: MSK - Bone & Soft Tissue: no. 4465 |
| Persistent Identifier | http://hdl.handle.net/10722/229771 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Lee, EYP | - |
| dc.contributor.author | He, J | - |
| dc.contributor.author | Perucho, JAU | - |
| dc.contributor.author | Chan, Q | - |
| dc.date.accessioned | 2016-08-23T14:13:10Z | - |
| dc.date.available | 2016-08-23T14:13:10Z | - |
| dc.date.issued | 2016 | - |
| dc.identifier.citation | The 24th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2016), Singapore, 7-13 May 2016. | - |
| dc.identifier.uri | http://hdl.handle.net/10722/229771 | - |
| dc.description | Electronic Poster Session: MSK - Bone & Soft Tissue: no. 4465 | - |
| dc.description.abstract | Intravoxel incoherent motion (IVIM) diffusion-weighted MRI offers the unique opportunity to simultaneously study the diffusion and perfusion changes in the bone marrow following whole-pelvis radiotherapy. We prospectively studied twenty-eight patients with cervical cancer who had paired IVIM MRI examinations before and at week-4 of treatment. We observed a distinctive positive trend of D (true diffusion coefficient) in patients who suffered hematological toxicity (HT), whilst D remained relatively stable in patients who did not suffer HT. In addition, f (perfusion fraction) increased following treatment, but this pattern was not unique to patients who suffered HT. | - |
| dc.language | eng | - |
| dc.relation.ispartof | Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine, ISMRM 2016 | - |
| dc.title | Radiation-induced early temporal changes of IVIM-based diffusion and perfusion patterns of bone marrow predict the likelihood of hematological toxicity | - |
| dc.type | Conference_Paper | - |
| dc.identifier.email | Lee, EYP: eyplee77@hku.hk | - |
| dc.identifier.authority | Lee, EYP=rp01456 | - |
| dc.identifier.hkuros | 260020 | - |