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- Publisher Website: 10.1002/jmri.24808
- Scopus: eid_2-s2.0-84937552530
- PMID: 25413245
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Article: Relationship between intravoxel incoherent motion diffusion-weighted MRI and dynamic contrast-enhanced MRI in tissue perfusion of cervical cancers
Title | Relationship between intravoxel incoherent motion diffusion-weighted MRI and dynamic contrast-enhanced MRI in tissue perfusion of cervical cancers |
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Authors | |
Keywords | perfusion intravoxel incoherent motion DCE-MRI cervical cancer IVIM |
Issue Date | 2015 |
Citation | Journal of Magnetic Resonance Imaging, 2015, v. 42, n. 2, p. 454-459 How to Cite? |
Abstract | © 2014 Wiley Periodicals, Inc.Purpose To investigate the relationship between intravoxel incoherent motion (IVIM) diffusion-weighted magnetic resonance imaging (MRI) and dynamic contrast-enhanced MRI (DCE-MRI) in cervical cancer perfusion. Materials and Methods Prospective newly diagnosed cervical cancer patients underwent diffusion-weighted MRI (13 b-values: 1-1000 s/mm2) and DCE-MRI. The IVIM perfusion parameters, perfusion fraction (f), pseudodiffusion coefficient (D∗), and flow-related parameter (fD∗), were derived from a biexponential decay model. DCE-MRI was analyzed with a pharmacokinetic model and signal-time curve to derive the amplitude factor (A), estimated volume transfer constant between blood plasma, and the extravascular extracellular space ( |
Persistent Identifier | http://hdl.handle.net/10722/239764 |
ISSN | 2023 Impact Factor: 3.3 2023 SCImago Journal Rankings: 1.339 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Lee, Elaine Yuen Phin | - |
dc.contributor.author | Hui, Edward Sai Kam | - |
dc.contributor.author | Chan, Karen Kar Loen | - |
dc.contributor.author | Tse, Ka Yu | - |
dc.contributor.author | Kwong, Wai Kay | - |
dc.contributor.author | Chang, Tien Yee | - |
dc.contributor.author | Chan, Queenie | - |
dc.contributor.author | Khong, Pek Lan | - |
dc.date.accessioned | 2017-04-03T02:41:21Z | - |
dc.date.available | 2017-04-03T02:41:21Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Journal of Magnetic Resonance Imaging, 2015, v. 42, n. 2, p. 454-459 | - |
dc.identifier.issn | 1053-1807 | - |
dc.identifier.uri | http://hdl.handle.net/10722/239764 | - |
dc.description.abstract | © 2014 Wiley Periodicals, Inc.Purpose To investigate the relationship between intravoxel incoherent motion (IVIM) diffusion-weighted magnetic resonance imaging (MRI) and dynamic contrast-enhanced MRI (DCE-MRI) in cervical cancer perfusion. Materials and Methods Prospective newly diagnosed cervical cancer patients underwent diffusion-weighted MRI (13 b-values: 1-1000 s/mm<sup>2</sup>) and DCE-MRI. The IVIM perfusion parameters, perfusion fraction (f), pseudodiffusion coefficient (D∗), and flow-related parameter (fD∗), were derived from a biexponential decay model. DCE-MRI was analyzed with a pharmacokinetic model and signal-time curve to derive the amplitude factor (A), estimated volume transfer constant between blood plasma, and the extravascular extracellular space (<inf>est</inf>K<sup>trans</sup>), maximum relative enhancement (MaxRE), and area under the signal-time curve (AUC). Spearman's rank correlation coefficient (r) evaluated the correlative relationships. Results The f = 13.51%-±-1.76%, D∗ = 71.72-±-7.55 × 10<sup>-3</sup> mm<sup>2</sup>/s, fD∗ = 9.64-±-1.28 × 10<sup>-3</sup> mm<sup>2</sup>/s, A = 1.41-±-0.43, <inf>est</inf>K<sup>trans</sup> = 0.19-±-0.06 s<sup>-1</sup>, MaxRE of 120.02-±-21.07%, and AUC 212,393-±-54,423 was found in 25 cervical cancer patients. Statistically significant positive correlations were found between fD∗ and <inf>est</inf>K<sup>trans</sup> (r = 0.42, P = 0.038), fD∗ and A (r = 0.50, P = 0.011), fD∗ and MaxRE (r = 0.52, P = 0.008), f and AUC (r = 0.58, P = 0.003). Conclusion: The IVIM perfusion parameters showed moderate to good correlations with quantitative and semiquantitative perfusion parameters derived from DCE-MRI in cervical cancer. | - |
dc.language | eng | - |
dc.relation.ispartof | Journal of Magnetic Resonance Imaging | - |
dc.subject | perfusion | - |
dc.subject | intravoxel incoherent motion | - |
dc.subject | DCE-MRI | - |
dc.subject | cervical cancer | - |
dc.subject | IVIM | - |
dc.title | Relationship between intravoxel incoherent motion diffusion-weighted MRI and dynamic contrast-enhanced MRI in tissue perfusion of cervical cancers | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1002/jmri.24808 | - |
dc.identifier.pmid | 25413245 | - |
dc.identifier.scopus | eid_2-s2.0-84937552530 | - |
dc.identifier.hkuros | 241731 | - |
dc.identifier.volume | 42 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 454 | - |
dc.identifier.epage | 459 | - |
dc.identifier.eissn | 1522-2586 | - |
dc.identifier.isi | WOS:000358258600024 | - |
dc.identifier.issnl | 1053-1807 | - |