File Download
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.3390/ijms18081723
- Scopus: eid_2-s2.0-85027066010
- PMID: 28783130
- WOS: WOS:000408897400124
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Shear Bond Strength and Remineralisation Effect of a Casein Phosphopeptide-Amorphous Calcium Phosphate-Modified Glass Ionomer Cement on Artificial “Caries-Affected” Dentine
Title | Shear Bond Strength and Remineralisation Effect of a Casein Phosphopeptide-Amorphous Calcium Phosphate-Modified Glass Ionomer Cement on Artificial “Caries-Affected” Dentine |
---|---|
Authors | |
Keywords | Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) Glass ionomer Remineralisation Shear bond strength |
Issue Date | 2017 |
Publisher | Molecular Diversity Preservation International. The Journal's web site is located at http://www.mdpi.org/ijms |
Citation | International Journal of Molecular Sciences, 2017, v. 18 n. 8, article no. 1723 How to Cite? |
Abstract | This study investigated the effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP)-modified glass ionomer cement (GIC) on shear bond strength (SBS) and remineralisation of artificial “caries-affected” dentine. Human dentine slices were demineralised and allocated to three groups: group 1, conventional GIC; group 2, CPP-ACP-modified GIC; and group 3, resin-modified GIC. The SBS was measured using a universal testing machine (n = 16 per group). Remaining samples (n = 8 per group) were subjected to pH-cycling for 28 days. After pH-cycling, lesion depth and micro-mechanical properties at the sample-bonding interface were investigated using micro-computed tomography (micro-CT) and nano-indentation, respectively. The SBS for groups 1 to 3 were 4.6 ± 1.5 MPa, 4.2 ± 1.1 MPa, and 5.9 ± 1.9 MPa, respectively (p = 0.007; group 1, group 2 < group 3). Lesion depths determined by micro-CT for groups 1 to 3 were 186 ± 8 µm, 149 ± 14 µm, and 178 ± 8 µm, respectively (p < 0.001; group 2 < group 1, group 3). The mean (±SD, standard deviation) nano-hardness values for groups 1 to 3 were 0.85 ± 0.22 GPa, 1.14 ± 0.21 GPa, and 0.81 ± 0.09 GPa, respectively (p = 0.003; group 1, group 3 < group 2). The mean (±SD) elastic moduli for groups 1 to 3 were 1.70 ± 0.33 GPa, 2.35 ± 0.44 GPa, and 1.59 ± 0.13 GPa, respectively (p < 0.001; group 1, group 3 < group 2). The results suggest that the incorporation of CPP-ACP into GIC does not adversely affect the adhesion to artificial caries-affected dentine. Furthermore, CPP-ACP-modified GIC is superior to conventional GIC in promoting dentine remineralisation. |
Persistent Identifier | http://hdl.handle.net/10722/244779 |
ISSN | 2023 Impact Factor: 4.9 2023 SCImago Journal Rankings: 1.179 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Zhou, Z | - |
dc.contributor.author | Burrow, MF | - |
dc.contributor.author | Lo, ECM | - |
dc.contributor.author | Chu, CH | - |
dc.date.accessioned | 2017-09-18T01:58:54Z | - |
dc.date.available | 2017-09-18T01:58:54Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | International Journal of Molecular Sciences, 2017, v. 18 n. 8, article no. 1723 | - |
dc.identifier.issn | 1422-0067 | - |
dc.identifier.uri | http://hdl.handle.net/10722/244779 | - |
dc.description.abstract | This study investigated the effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP)-modified glass ionomer cement (GIC) on shear bond strength (SBS) and remineralisation of artificial “caries-affected” dentine. Human dentine slices were demineralised and allocated to three groups: group 1, conventional GIC; group 2, CPP-ACP-modified GIC; and group 3, resin-modified GIC. The SBS was measured using a universal testing machine (n = 16 per group). Remaining samples (n = 8 per group) were subjected to pH-cycling for 28 days. After pH-cycling, lesion depth and micro-mechanical properties at the sample-bonding interface were investigated using micro-computed tomography (micro-CT) and nano-indentation, respectively. The SBS for groups 1 to 3 were 4.6 ± 1.5 MPa, 4.2 ± 1.1 MPa, and 5.9 ± 1.9 MPa, respectively (p = 0.007; group 1, group 2 < group 3). Lesion depths determined by micro-CT for groups 1 to 3 were 186 ± 8 µm, 149 ± 14 µm, and 178 ± 8 µm, respectively (p < 0.001; group 2 < group 1, group 3). The mean (±SD, standard deviation) nano-hardness values for groups 1 to 3 were 0.85 ± 0.22 GPa, 1.14 ± 0.21 GPa, and 0.81 ± 0.09 GPa, respectively (p = 0.003; group 1, group 3 < group 2). The mean (±SD) elastic moduli for groups 1 to 3 were 1.70 ± 0.33 GPa, 2.35 ± 0.44 GPa, and 1.59 ± 0.13 GPa, respectively (p < 0.001; group 1, group 3 < group 2). The results suggest that the incorporation of CPP-ACP into GIC does not adversely affect the adhesion to artificial caries-affected dentine. Furthermore, CPP-ACP-modified GIC is superior to conventional GIC in promoting dentine remineralisation. | - |
dc.language | eng | - |
dc.publisher | Molecular Diversity Preservation International. The Journal's web site is located at http://www.mdpi.org/ijms | - |
dc.relation.ispartof | International Journal of Molecular Sciences | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) | - |
dc.subject | Glass ionomer | - |
dc.subject | Remineralisation | - |
dc.subject | Shear bond strength | - |
dc.title | Shear Bond Strength and Remineralisation Effect of a Casein Phosphopeptide-Amorphous Calcium Phosphate-Modified Glass Ionomer Cement on Artificial “Caries-Affected” Dentine | - |
dc.type | Article | - |
dc.identifier.email | Burrow, MF: mfburr58@hku.hk | - |
dc.identifier.email | Lo, ECM: edward-lo@hku.hk | - |
dc.identifier.email | Chu, CH: chchu@hku.hk | - |
dc.identifier.authority | Burrow, MF=rp01306 | - |
dc.identifier.authority | Lo, ECM=rp00015 | - |
dc.identifier.authority | Chu, CH=rp00022 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.3390/ijms18081723 | - |
dc.identifier.pmid | 28783130 | - |
dc.identifier.pmcid | PMC5578113 | - |
dc.identifier.scopus | eid_2-s2.0-85027066010 | - |
dc.identifier.hkuros | 276274 | - |
dc.identifier.volume | 18 | - |
dc.identifier.issue | 8 | - |
dc.identifier.spage | article no. 1723 | - |
dc.identifier.epage | article no. 1723 | - |
dc.identifier.isi | WOS:000408897400124 | - |
dc.publisher.place | Switzerland | - |
dc.identifier.issnl | 1422-0067 | - |