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Article: Formation of Fluorohydroxyapatite with Silver Diamine Fluoride

TitleFormation of Fluorohydroxyapatite with Silver Diamine Fluoride
Authors
Keywordscalcium
dental caries
fluor-hydroxylapatite
hydroxylapatite
phosphates
tooth remineralization
Issue Date2017
PublisherSage Publications, Inc. The Journal's web site is located at http://jdr.sagepub.com/
Citation
Journal of Dental Research, 2017, v. 96 n. 10, p. 1122-1128 How to Cite?
AbstractThis study investigated the softening and erosive effects of various paediatric over-the-counter (OTC) oral liquids on deciduous teeth. Twenty sectioned and polished deciduous enamel blocks were ground on the buccal surface (2 × 2 mm²) and randomly divided into five groups, immersed into four commercially-available paediatric OTC oral liquids (two for paracetamol, both sugared; and two for chlorpheniramine, one sugared and one sugar-free), with deionized water as control. The pH of the oral liquids ranged from 2.50 to 5.77. Each block was immersed into the test or control groups for 15 s, rinsed with deionized water, and Vickers micro-hardness (n = 5) was measured. After twenty cycles of immersion and hardness measurements, Scanning Electron Microscope (SEM) and Energy Dispersive X-ray Spectrometry (EDS) were used to evaluate the surface morphology and chemistry of the tooth blocks, respectively. The pH values of the liquids were also recorded. Rapidly descending trends in the micro-hardness ratios of the four test groups were observed that were statistically different from the control group (p < 0.001). EDS showed an increase of Ca/C ratio after drug immersion, whereas SEM showed an enamel loss in all the test groups. Paediatric OTC oral liquids could significantly soften the enamel and render them more susceptible to caries, such that the formulation of the oral liquids is the major factor.
Persistent Identifierhttp://hdl.handle.net/10722/244798
ISSN
2020 Impact Factor: 6.116
2015 SCImago Journal Rankings: 1.714
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorMei, ML-
dc.contributor.authorNudelman, F-
dc.contributor.authorMarzec, B-
dc.contributor.authorWalker, J.M.-
dc.contributor.authorLo, ECM-
dc.contributor.authorWalls, AW-
dc.contributor.authorChu, CH-
dc.date.accessioned2017-09-18T01:59:15Z-
dc.date.available2017-09-18T01:59:15Z-
dc.date.issued2017-
dc.identifier.citationJournal of Dental Research, 2017, v. 96 n. 10, p. 1122-1128-
dc.identifier.issn0022-0345-
dc.identifier.urihttp://hdl.handle.net/10722/244798-
dc.description.abstractThis study investigated the softening and erosive effects of various paediatric over-the-counter (OTC) oral liquids on deciduous teeth. Twenty sectioned and polished deciduous enamel blocks were ground on the buccal surface (2 × 2 mm²) and randomly divided into five groups, immersed into four commercially-available paediatric OTC oral liquids (two for paracetamol, both sugared; and two for chlorpheniramine, one sugared and one sugar-free), with deionized water as control. The pH of the oral liquids ranged from 2.50 to 5.77. Each block was immersed into the test or control groups for 15 s, rinsed with deionized water, and Vickers micro-hardness (n = 5) was measured. After twenty cycles of immersion and hardness measurements, Scanning Electron Microscope (SEM) and Energy Dispersive X-ray Spectrometry (EDS) were used to evaluate the surface morphology and chemistry of the tooth blocks, respectively. The pH values of the liquids were also recorded. Rapidly descending trends in the micro-hardness ratios of the four test groups were observed that were statistically different from the control group (p < 0.001). EDS showed an increase of Ca/C ratio after drug immersion, whereas SEM showed an enamel loss in all the test groups. Paediatric OTC oral liquids could significantly soften the enamel and render them more susceptible to caries, such that the formulation of the oral liquids is the major factor.-
dc.languageeng-
dc.publisherSage Publications, Inc. The Journal's web site is located at http://jdr.sagepub.com/-
dc.relation.ispartofJournal of Dental Research-
dc.rightsSage Publications, Inc. The Journal's web site is located at http://jdr.sagepub.com/-
dc.subjectcalcium-
dc.subjectdental caries-
dc.subjectfluor-hydroxylapatite-
dc.subjecthydroxylapatite-
dc.subjectphosphates-
dc.subjecttooth remineralization-
dc.titleFormation of Fluorohydroxyapatite with Silver Diamine Fluoride-
dc.typeArticle-
dc.identifier.emailLo, ECM: edward-lo@hku.hk-
dc.identifier.emailChu, CH: chchu@hku.hk-
dc.identifier.authorityLo, ECM=rp00015-
dc.identifier.authorityChu, CH=rp00022-
dc.identifier.doi10.1177/0022034517709738-
dc.identifier.pmid28521107-
dc.identifier.pmcidPMC5582683-
dc.identifier.scopuseid_2-s2.0-85027884216-
dc.identifier.hkuros278154-
dc.identifier.volume96-
dc.identifier.issue10-
dc.identifier.spage1122-
dc.identifier.epage1128-
dc.identifier.isiWOS:000408048000009-
dc.publisher.placeUnited States-
dc.identifier.issnl0022-0345-

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