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Conference Paper: Histogram analysis of intravoxel incoherent motion parameters in assessing tumour diffusion and perfusion heterogeneity in cervical cancer before and after chemoradiotherapy
Title | Histogram analysis of intravoxel incoherent motion parameters in assessing tumour diffusion and perfusion heterogeneity in cervical cancer before and after chemoradiotherapy |
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Authors | |
Issue Date | 2017 |
Publisher | International Society for Magnetic Resonance in Medicine (ISMRM). |
Citation | The International Society for Magnetic Resonance in Medicine (ISMRM) 25th Annual Meeting & Exhibition, Honolulu, HI, 22-27 April 2017 How to Cite? |
Abstract | Histogram analysis of intravoxel incoherent motion (IVIM) diffusion-weighted MRI (DWI) could be a promising quantitative approach in assessing tumour heterogeneity. We retrospectively studied twenty-five patients with cervical cancer who had paired IVIM MRI examinations before and at week-4 of chemoradiotherapy treatment (CRT). We observed histogram skewness and kurtosis significantly decreased while mean and all percentiles significantly increased in apparent diffusion coefficient (ADC), true diffusion coefficient (D) and perfusion fraction (f) following treatment. Furthermore, these significant differences were not correlated with a change in primary tumour volume (PTV) following treatment. |
Persistent Identifier | http://hdl.handle.net/10722/245515 |
DC Field | Value | Language |
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dc.contributor.author | Perucho, JAU | - |
dc.contributor.author | Lee, EYP | - |
dc.contributor.author | Chan, WCL | - |
dc.contributor.author | Gong, N | - |
dc.contributor.author | Chan, Q | - |
dc.date.accessioned | 2017-09-18T02:12:04Z | - |
dc.date.available | 2017-09-18T02:12:04Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | The International Society for Magnetic Resonance in Medicine (ISMRM) 25th Annual Meeting & Exhibition, Honolulu, HI, 22-27 April 2017 | - |
dc.identifier.uri | http://hdl.handle.net/10722/245515 | - |
dc.description.abstract | Histogram analysis of intravoxel incoherent motion (IVIM) diffusion-weighted MRI (DWI) could be a promising quantitative approach in assessing tumour heterogeneity. We retrospectively studied twenty-five patients with cervical cancer who had paired IVIM MRI examinations before and at week-4 of chemoradiotherapy treatment (CRT). We observed histogram skewness and kurtosis significantly decreased while mean and all percentiles significantly increased in apparent diffusion coefficient (ADC), true diffusion coefficient (D) and perfusion fraction (f) following treatment. Furthermore, these significant differences were not correlated with a change in primary tumour volume (PTV) following treatment. | - |
dc.language | eng | - |
dc.publisher | International Society for Magnetic Resonance in Medicine (ISMRM). | - |
dc.relation.ispartof | The International Society for Magnetic Resonance in Medicine (ISMRM) Annual Meeting & Exhibition | - |
dc.title | Histogram analysis of intravoxel incoherent motion parameters in assessing tumour diffusion and perfusion heterogeneity in cervical cancer before and after chemoradiotherapy | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Lee, EYP: eyplee77@hku.hk | - |
dc.identifier.authority | Lee, EYP=rp01456 | - |
dc.identifier.hkuros | 278822 | - |
dc.publisher.place | Honolulu, HI | - |