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- Publisher Website: 10.1016/j.ijsu.2017.11.005
- Scopus: eid_2-s2.0-85038003210
- WOS: WOS:000419839600005
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Article: Factors Affecting The Under-diagnosis Of Atypical Ductal Hyperplasia Diagnosed By Core Needle Biopsies – A 10-year Retrospective Study And Review Of The Literature
Title | Factors Affecting The Under-diagnosis Of Atypical Ductal Hyperplasia Diagnosed By Core Needle Biopsies – A 10-year Retrospective Study And Review Of The Literature |
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Authors | |
Keywords | Atypical ductal hyperplasia Breast neoplasms Core needle biopsy |
Issue Date | 2018 |
Citation | International Journal of Surgery, 2018, v. 49, p. 27-31 How to Cite? |
Abstract | INTRODUCTION: Due to the possibility of underestimation, surgical excision is usually offered to patients with atypical ductal hyperplasia (ADH) diagnosed with core needle biopsy (CNB). Here we review the 10-year data of patients with ADH diagnosed by CNB, aiming to identify the factors associated with under-diagnosis. METHODS: Retrospective review of database from 1st Jan 2005 to 31st Dec 2014 was performed; patients with ADH diagnosed by CNB were identified. Diagnosis upgrade rate and its risk factors were evaluated. RESULTS: 104 patients were found to have ADH on CNB, 101 patients received excisional biopsy while 3 patients refused operation. 34 patients had ductal carcinoma in situ (DCIS) after excision, 6 had invasive ductal carcinoma, 1 had lobular carcinoma in situ and 1 had angiosarcoma. CNB under-diagnosed up to 41.6% of malignant lesions. Breast mass on presentation and suspicious mammograms (BIRADS ≥ 4) are associated with diagnosis upgrade (P = 0.0005, 0.0001). Literature review of 39 studies between 1997 and 2017 revealed 3125 excision procedures performed for ADH diagnosed by CNB, the pooled median diagnosis upgrade rate was 25% (Range 4-54%). CONCLUSION: We recommend excision in all patients with ADH diagnosed by CNB, especially in patients with suspicious mammographic features. |
Persistent Identifier | http://hdl.handle.net/10722/251809 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Co, THM | - |
dc.contributor.author | Kwong, A | - |
dc.contributor.author | Shek, T | - |
dc.date.accessioned | 2018-03-19T07:01:37Z | - |
dc.date.available | 2018-03-19T07:01:37Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | International Journal of Surgery, 2018, v. 49, p. 27-31 | - |
dc.identifier.uri | http://hdl.handle.net/10722/251809 | - |
dc.description.abstract | INTRODUCTION: Due to the possibility of underestimation, surgical excision is usually offered to patients with atypical ductal hyperplasia (ADH) diagnosed with core needle biopsy (CNB). Here we review the 10-year data of patients with ADH diagnosed by CNB, aiming to identify the factors associated with under-diagnosis. METHODS: Retrospective review of database from 1st Jan 2005 to 31st Dec 2014 was performed; patients with ADH diagnosed by CNB were identified. Diagnosis upgrade rate and its risk factors were evaluated. RESULTS: 104 patients were found to have ADH on CNB, 101 patients received excisional biopsy while 3 patients refused operation. 34 patients had ductal carcinoma in situ (DCIS) after excision, 6 had invasive ductal carcinoma, 1 had lobular carcinoma in situ and 1 had angiosarcoma. CNB under-diagnosed up to 41.6% of malignant lesions. Breast mass on presentation and suspicious mammograms (BIRADS ≥ 4) are associated with diagnosis upgrade (P = 0.0005, 0.0001). Literature review of 39 studies between 1997 and 2017 revealed 3125 excision procedures performed for ADH diagnosed by CNB, the pooled median diagnosis upgrade rate was 25% (Range 4-54%). CONCLUSION: We recommend excision in all patients with ADH diagnosed by CNB, especially in patients with suspicious mammographic features. | - |
dc.language | eng | - |
dc.relation.ispartof | International Journal of Surgery | - |
dc.subject | Atypical ductal hyperplasia | - |
dc.subject | Breast neoplasms | - |
dc.subject | Core needle biopsy | - |
dc.title | Factors Affecting The Under-diagnosis Of Atypical Ductal Hyperplasia Diagnosed By Core Needle Biopsies – A 10-year Retrospective Study And Review Of The Literature | - |
dc.type | Article | - |
dc.identifier.email | Co, THM: mcth@hku.hk | - |
dc.identifier.email | Kwong, A: avakwong@hku.hk | - |
dc.identifier.authority | Co, THM=rp02101 | - |
dc.identifier.authority | Kwong, A=rp01734 | - |
dc.identifier.doi | 10.1016/j.ijsu.2017.11.005 | - |
dc.identifier.scopus | eid_2-s2.0-85038003210 | - |
dc.identifier.hkuros | 284562 | - |
dc.identifier.volume | 49 | - |
dc.identifier.spage | 27 | - |
dc.identifier.epage | 31 | - |
dc.identifier.isi | WOS:000419839600005 | - |