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Conference Paper: Optogenetic fMRI Application: Dissecting Brain Networks & Properties

TitleOptogenetic fMRI Application: Dissecting Brain Networks & Properties
Authors
Issue Date2017
PublisherThe International Society for Magnetic Resonance in Medicine.
Citation
ISMRM 25th Annual Meeting & Exhibition, Honolulu, HI, 22-27 April 2017 How to Cite?
AbstractUnderstanding how individual cells and complex brain networks interact in both time and space has been one of the grand challenges in the 21st century. In 2010, Lee et. al. have demonstrated that optogenetic fMRI (ofMRI) within the living mammalian brain reveals BOLD signals in downstream targets distant from the stimulation site, indicating that this approach can be used to map the global effects of controlling a local cell-type specific neuronal population. Since then, multiple studies have utilized ofMRI to dissect brain networks and properties. In this session, technical considerations in the application of ofMRI will be examined. Studies dissecting brain networks and properties using ofMRI will be reviewed. The opportunities and challenges will be discussed.
Persistent Identifierhttp://hdl.handle.net/10722/257593

 

DC FieldValueLanguage
dc.contributor.authorChan, RW-
dc.date.accessioned2018-08-08T04:25:40Z-
dc.date.available2018-08-08T04:25:40Z-
dc.date.issued2017-
dc.identifier.citationISMRM 25th Annual Meeting & Exhibition, Honolulu, HI, 22-27 April 2017-
dc.identifier.urihttp://hdl.handle.net/10722/257593-
dc.description.abstractUnderstanding how individual cells and complex brain networks interact in both time and space has been one of the grand challenges in the 21st century. In 2010, Lee et. al. have demonstrated that optogenetic fMRI (ofMRI) within the living mammalian brain reveals BOLD signals in downstream targets distant from the stimulation site, indicating that this approach can be used to map the global effects of controlling a local cell-type specific neuronal population. Since then, multiple studies have utilized ofMRI to dissect brain networks and properties. In this session, technical considerations in the application of ofMRI will be examined. Studies dissecting brain networks and properties using ofMRI will be reviewed. The opportunities and challenges will be discussed.-
dc.languageeng-
dc.publisherThe International Society for Magnetic Resonance in Medicine. -
dc.relation.ispartofISMRM Annual Meeting & Exhibition-
dc.titleOptogenetic fMRI Application: Dissecting Brain Networks & Properties-
dc.typeConference_Paper-
dc.identifier.emailChan, RW: russchan@connect.hku.hk-
dc.identifier.hkuros275513-
dc.publisher.placeHonolulu, HI-

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