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- Publisher Website: 10.1016/S1499-3872(17)60039-0
- Scopus: eid_2-s2.0-85027681575
- PMID: 28823368
- WOS: WOS:000407663500006
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Article: Hepatopancreatoduodenectomy for advanced hepatobiliary malignancies: a single-center experience
Title | Hepatopancreatoduodenectomy for advanced hepatobiliary malignancies: a single-center experience |
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Authors | |
Keywords | Hepatectomy Hepatopancreatoduodenectomy Malignancy Pancreaticojejunostomy Pancreatoduodenectomy |
Issue Date | 2017 |
Publisher | Elsevier for the First Affiliated Hospital, Zhejiang University School of Medicine. The Journal's web site is located at http://www.hbpdint.com/ |
Citation | Hepatobiliary & Pancreatic Diseases International, 2017, v. 16 n. 4, p. 382-386 How to Cite? |
Abstract | Background Hepatopancreatoduodenectomy is a complicated and challenging procedure but necessary for curative resection for advanced hepatobiliary malignancies. This retrospective study was to examine the safety and survival outcomes of hepatopancreatoduodenectomy in our center. Methods Prospectively collected data of 12 patients who underwent hepatopancreatoduodenectomy for advanced hepatobiliary malignancies in our hospital from January 1998 to December 2014 were analyzed. The primary endpoints are treatment-related morbidity and mortality and the secondary endpoints are overall survival and disease-free survival. Results Curative resection was achieved in 11 (91.7%) patients. Complications developed in 10 (83.3%) patients. Three hospital deaths resulted from multiorgan failure secondary to postoperative pancreatic fistula or hepaticojejunostomy leakage. Six of the nine remaining patients had disease recurrence. The nine patients had a median survival of 39.8 (5.3–151.8) months. The 1-, 3- and 5-year overall survival rates were 66.7%, 55.6% and 27.8%, respectively. The corresponding disease-free survival rates were 55.6%, 44.4% and 29.6%, respectively. Conclusions Morbidity and mortality after hepatopancreatoduodenectomy were significant. With R0 resection, the 5-year overall survival and disease-free survival rates were 27.8% and 29.6%, respectively. |
Persistent Identifier | http://hdl.handle.net/10722/259538 |
ISSN | 2023 Impact Factor: 3.6 2023 SCImago Journal Rankings: 0.720 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Dai, WC | - |
dc.contributor.author | Chok, KSH | - |
dc.contributor.author | Cheung, TT | - |
dc.contributor.author | Chan, ACY | - |
dc.contributor.author | Chan, SC | - |
dc.contributor.author | Lo, CM | - |
dc.date.accessioned | 2018-09-03T04:09:34Z | - |
dc.date.available | 2018-09-03T04:09:34Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | Hepatobiliary & Pancreatic Diseases International, 2017, v. 16 n. 4, p. 382-386 | - |
dc.identifier.issn | 1499-3872 | - |
dc.identifier.uri | http://hdl.handle.net/10722/259538 | - |
dc.description.abstract | Background Hepatopancreatoduodenectomy is a complicated and challenging procedure but necessary for curative resection for advanced hepatobiliary malignancies. This retrospective study was to examine the safety and survival outcomes of hepatopancreatoduodenectomy in our center. Methods Prospectively collected data of 12 patients who underwent hepatopancreatoduodenectomy for advanced hepatobiliary malignancies in our hospital from January 1998 to December 2014 were analyzed. The primary endpoints are treatment-related morbidity and mortality and the secondary endpoints are overall survival and disease-free survival. Results Curative resection was achieved in 11 (91.7%) patients. Complications developed in 10 (83.3%) patients. Three hospital deaths resulted from multiorgan failure secondary to postoperative pancreatic fistula or hepaticojejunostomy leakage. Six of the nine remaining patients had disease recurrence. The nine patients had a median survival of 39.8 (5.3–151.8) months. The 1-, 3- and 5-year overall survival rates were 66.7%, 55.6% and 27.8%, respectively. The corresponding disease-free survival rates were 55.6%, 44.4% and 29.6%, respectively. Conclusions Morbidity and mortality after hepatopancreatoduodenectomy were significant. With R0 resection, the 5-year overall survival and disease-free survival rates were 27.8% and 29.6%, respectively. | - |
dc.language | eng | - |
dc.publisher | Elsevier for the First Affiliated Hospital, Zhejiang University School of Medicine. The Journal's web site is located at http://www.hbpdint.com/ | - |
dc.relation.ispartof | Hepatobiliary & Pancreatic Diseases International | - |
dc.subject | Hepatectomy | - |
dc.subject | Hepatopancreatoduodenectomy | - |
dc.subject | Malignancy | - |
dc.subject | Pancreaticojejunostomy | - |
dc.subject | Pancreatoduodenectomy | - |
dc.title | Hepatopancreatoduodenectomy for advanced hepatobiliary malignancies: a single-center experience | - |
dc.type | Article | - |
dc.identifier.email | Dai, WC: daiwc@HKUCC-COM.hku.hk | - |
dc.identifier.email | Chok, KSH: chok6275@hku.hk | - |
dc.identifier.email | Cheung, TT: cheung68@hku.hk | - |
dc.identifier.email | Chan, ACY: acchan@hku.hk | - |
dc.identifier.email | Chan, SC: chanlsc@hkucc.hku.hk | - |
dc.identifier.email | Lo, CM: chungmlo@hkucc.hku.hk | - |
dc.identifier.authority | Chok, KSH=rp02110 | - |
dc.identifier.authority | Cheung, TT=rp02129 | - |
dc.identifier.authority | Chan, ACY=rp00310 | - |
dc.identifier.authority | Chan, SC=rp01568 | - |
dc.identifier.authority | Lo, CM=rp00412 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/S1499-3872(17)60039-0 | - |
dc.identifier.pmid | 28823368 | - |
dc.identifier.scopus | eid_2-s2.0-85027681575 | - |
dc.identifier.hkuros | 288609 | - |
dc.identifier.volume | 16 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 382 | - |
dc.identifier.epage | 386 | - |
dc.identifier.isi | WOS:000407663500006 | - |
dc.publisher.place | China | - |
dc.identifier.issnl | 2352-9377 | - |