File Download
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1177/1557988319835139
- Scopus: eid_2-s2.0-85062483220
- PMID: 30836839
- WOS: WOS:000460392300001
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Prospective study on sexual dysfunction in male Chinese liver transplant recipients
Title | Prospective study on sexual dysfunction in male Chinese liver transplant recipients |
---|---|
Authors | |
Keywords | liver transplantation erectile dysfunction hypogonadism end-stage liver disease sexual dysfunction |
Issue Date | 2019 |
Publisher | SAGE Publications (UK and US): Open Access Titles. The Journal's web site is located at http://www.sagepub.co.uk/editorDetails.nav?contribId=522646 |
Citation | American Journal of Men's Health, 2019, v. 13 n. 2, article no. 1557988319835139 How to Cite? |
Abstract | In patients with end-stage liver disease, hypogonadism and erectile dysfunction are often seen. This study was to determine the incidence of erectile dysfunction before and after liver transplantation (LT) with correlation to change in sex hormone levels from a Chinese cohort. This prospective longitudinal study was registered with The University of Hong Kong Clinical Trials Centre (HKUCTR-1563). The Institutional Review Board approval number is UW-12-273. The study period was from January 2012 to December 2016. Adult male patients with end-stage liver disease enlisted for LT were recruited on informed written consent. All recruited patients were to complete a cross-sectional cohort questionnaire—International Index of Erectile Function, version 5 (IIEF5)—and to receive serum sex hormone checks before and after LT. Twenty-eight patients who underwent LT were included in the analysis. The included patients had significantly reduced prolactin (p < .001) and 17-beta-estradiol (p = .024) after LT. There was also a significant drop of IIEF5 score at 1 month after LT, but the score returned to pre-LT level at 6 months. This study demonstrated that there was improvement in sex hormone levels after LT, namely, normalization of estradiol level and lowering of prolactin and progesterone levels. However, improvement in sex hormone levels did not translate into improvement of erectile dysfunction. |
Persistent Identifier | http://hdl.handle.net/10722/271249 |
ISSN | 2023 Impact Factor: 2.1 2023 SCImago Journal Rankings: 0.610 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chan, MY | - |
dc.contributor.author | Chok, KSH | - |
dc.contributor.author | Fung, JYY | - |
dc.contributor.author | Ng, SL | - |
dc.contributor.author | Yiu, MK | - |
dc.contributor.author | Lo, CM | - |
dc.date.accessioned | 2019-06-24T01:06:14Z | - |
dc.date.available | 2019-06-24T01:06:14Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | American Journal of Men's Health, 2019, v. 13 n. 2, article no. 1557988319835139 | - |
dc.identifier.issn | 1557-9883 | - |
dc.identifier.uri | http://hdl.handle.net/10722/271249 | - |
dc.description.abstract | In patients with end-stage liver disease, hypogonadism and erectile dysfunction are often seen. This study was to determine the incidence of erectile dysfunction before and after liver transplantation (LT) with correlation to change in sex hormone levels from a Chinese cohort. This prospective longitudinal study was registered with The University of Hong Kong Clinical Trials Centre (HKUCTR-1563). The Institutional Review Board approval number is UW-12-273. The study period was from January 2012 to December 2016. Adult male patients with end-stage liver disease enlisted for LT were recruited on informed written consent. All recruited patients were to complete a cross-sectional cohort questionnaire—International Index of Erectile Function, version 5 (IIEF5)—and to receive serum sex hormone checks before and after LT. Twenty-eight patients who underwent LT were included in the analysis. The included patients had significantly reduced prolactin (p < .001) and 17-beta-estradiol (p = .024) after LT. There was also a significant drop of IIEF5 score at 1 month after LT, but the score returned to pre-LT level at 6 months. This study demonstrated that there was improvement in sex hormone levels after LT, namely, normalization of estradiol level and lowering of prolactin and progesterone levels. However, improvement in sex hormone levels did not translate into improvement of erectile dysfunction. | - |
dc.language | eng | - |
dc.publisher | SAGE Publications (UK and US): Open Access Titles. The Journal's web site is located at http://www.sagepub.co.uk/editorDetails.nav?contribId=522646 | - |
dc.relation.ispartof | American Journal of Men's Health | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | liver transplantation | - |
dc.subject | erectile dysfunction | - |
dc.subject | hypogonadism | - |
dc.subject | end-stage liver disease | - |
dc.subject | sexual dysfunction | - |
dc.title | Prospective study on sexual dysfunction in male Chinese liver transplant recipients | - |
dc.type | Article | - |
dc.identifier.email | Chok, KSH: chok6275@hku.hk | - |
dc.identifier.email | Fung, JYY: jfung@hkucc.hku.hk | - |
dc.identifier.email | Yiu, MK: pmkyiu@hku.hk | - |
dc.identifier.email | Lo, CM: chungmlo@hkucc.hku.hk | - |
dc.identifier.authority | Chok, KSH=rp02110 | - |
dc.identifier.authority | Fung, JYY=rp00518 | - |
dc.identifier.authority | Lo, CM=rp00412 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1177/1557988319835139 | - |
dc.identifier.pmid | 30836839 | - |
dc.identifier.scopus | eid_2-s2.0-85062483220 | - |
dc.identifier.hkuros | 297968 | - |
dc.identifier.volume | 13 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 1557988319835139 | - |
dc.identifier.epage | 1557988319835139 | - |
dc.identifier.isi | WOS:000460392300001 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1557-9883 | - |