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- Publisher Website: 10.1155/2018/9847015
- Scopus: eid_2-s2.0-85062884142
- PMID: 30581475
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Article: Insights into Endothelial Progenitor Cells: Origin, Classification, Potentials, and Prospects
Title | Insights into Endothelial Progenitor Cells: Origin, Classification, Potentials, and Prospects |
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Authors | |
Keywords | adipose tissue apical papilla stem cell cell function cell isolation cerebrovascular disease |
Issue Date | 2018 |
Publisher | Hindawi Publishing Corporation. The Journal's web site is located at http://www.sage-hindawi.com/journals/sci/ |
Citation | Stem Cells International, 2018, v. 2018, p. article no. 9847015 How to Cite? |
Abstract | With the discovery of endothelial progenitor cells (EPCs) in the late 1990s, a paradigm shift in the concept of neoangiogenesis occurred. The identification of circulating EPCs in peripheral blood marked the beginning of a new era with enormous potential in the rapidly transforming regenerative field. Overwhelmed with the revelation, researchers across the globe focused on isolating, defining, and interpreting the role of EPCs in various physiological and pathological conditions. Consequently, controversies emerged regarding the isolation techniques and classification of EPCs. Nevertheless, the potential of using EPCs in tissue engineering as an angiogenic source has been extensively explored. Concomitantly, the impact of EPCs on various diseases, such as diabetes, cancer, and cardiovascular diseases, has been studied. Within the limitations of the current knowledge, this review attempts to delineate the concept of EPCs in a sequential manner from the speculative history to a definitive presence (origin, sources of EPCs, isolation, and identification) and significance of these EPCs. Additionally, this review is aimed at serving as a guide for investigators, identifying potential research gaps, and summarizing our current and future prospects regarding EPCs. |
Persistent Identifier | http://hdl.handle.net/10722/272125 |
ISSN | 2023 Impact Factor: 3.8 2023 SCImago Journal Rankings: 0.844 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | CHOPRA, H | - |
dc.contributor.author | Hung, MK | - |
dc.contributor.author | Kwong, DL | - |
dc.contributor.author | Zhang, CF | - |
dc.contributor.author | Pow, EHN | - |
dc.date.accessioned | 2019-07-20T10:36:09Z | - |
dc.date.available | 2019-07-20T10:36:09Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Stem Cells International, 2018, v. 2018, p. article no. 9847015 | - |
dc.identifier.issn | 1687-966X | - |
dc.identifier.uri | http://hdl.handle.net/10722/272125 | - |
dc.description.abstract | With the discovery of endothelial progenitor cells (EPCs) in the late 1990s, a paradigm shift in the concept of neoangiogenesis occurred. The identification of circulating EPCs in peripheral blood marked the beginning of a new era with enormous potential in the rapidly transforming regenerative field. Overwhelmed with the revelation, researchers across the globe focused on isolating, defining, and interpreting the role of EPCs in various physiological and pathological conditions. Consequently, controversies emerged regarding the isolation techniques and classification of EPCs. Nevertheless, the potential of using EPCs in tissue engineering as an angiogenic source has been extensively explored. Concomitantly, the impact of EPCs on various diseases, such as diabetes, cancer, and cardiovascular diseases, has been studied. Within the limitations of the current knowledge, this review attempts to delineate the concept of EPCs in a sequential manner from the speculative history to a definitive presence (origin, sources of EPCs, isolation, and identification) and significance of these EPCs. Additionally, this review is aimed at serving as a guide for investigators, identifying potential research gaps, and summarizing our current and future prospects regarding EPCs. | - |
dc.language | eng | - |
dc.publisher | Hindawi Publishing Corporation. The Journal's web site is located at http://www.sage-hindawi.com/journals/sci/ | - |
dc.relation.ispartof | Stem Cells International | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | adipose tissue | - |
dc.subject | apical papilla stem cell | - |
dc.subject | cell function | - |
dc.subject | cell isolation | - |
dc.subject | cerebrovascular disease | - |
dc.title | Insights into Endothelial Progenitor Cells: Origin, Classification, Potentials, and Prospects | - |
dc.type | Article | - |
dc.identifier.email | Kwong, DL: dlwkwong@hku.hk | - |
dc.identifier.email | Zhang, CF: zhangcf@hku.hk | - |
dc.identifier.email | Pow, EHN: ehnpow@hku.hk | - |
dc.identifier.authority | Kwong, DL=rp00414 | - |
dc.identifier.authority | Zhang, CF=rp01408 | - |
dc.identifier.authority | Pow, EHN=rp00030 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1155/2018/9847015 | - |
dc.identifier.pmid | 30581475 | - |
dc.identifier.pmcid | PMC6276490 | - |
dc.identifier.scopus | eid_2-s2.0-85062884142 | - |
dc.identifier.hkuros | 299053 | - |
dc.identifier.volume | 2018 | - |
dc.identifier.spage | article no. 9847015 | - |
dc.identifier.epage | article no. 9847015 | - |
dc.identifier.isi | WOS:000451873900001 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1687-966X | - |