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- Publisher Website: 10.1016/j.hbpd.2019.06.001
- Scopus: eid_2-s2.0-85067482014
- PMID: 31230961
- WOS: WOS:000481407500008
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Article: Donor ductal anomaly is not a contraindication to right liver lobe donation
Title | Donor ductal anomaly is not a contraindication to right liver lobe donation |
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Authors | |
Keywords | Living donor liver transplantation Right liver donation Biliary complications Cholangiograms Ductal anomaly |
Issue Date | 2019 |
Publisher | Elsevier for the First Affiliated Hospital, Zhejiang University School of Medicine. The Journal's web site is located at http://www.hbpdint.com/ |
Citation | Hepatobiliary & Pancreatic Diseases International, 2019, v. 18 n. 4, p. 343-347 How to Cite? |
Abstract | Background:
Data of living-donor liver transplantation (LDLT) suggested that donor ductal anomaly may contribute to postoperative biliary complications in recipients and in donors. This retrospective study aimed to determine if the occurrence of postoperative biliary stricture in donors or recipients in right-lobe LDLT (RLDLT) is related to donor biliary anatomy type.
Methods:
We analyzed our RLDLT recipients’ clinical data and those of their graft donors. The recipients were divided into 2 groups: with and without postoperative biliary stricture. The 2 groups were compared. The primary endpoints were donor biliary anatomy type and postoperative biliary complication incidence; the secondary endpoints were 1-, 3- and 5-year graft and patient survival rates.
Results:
Totally 127 patients were included in the study; 25 (19.7%) of them developed biliary anastomotic stricture. In these 25 patients, 16 had type A biliary anatomy, 3 had type B, 2 had type C, 3 had type D, and 1 had type E. In the 127 donors, 96 (75.6%) had type A biliary anatomy, 13 (10.2%) had type B, 6 (4.7%) had type C, 10 (7.9%) had type D, and 2 (1.6%) had type E. Biliary stricture was seen in 2 donors, who had type A biliary anatomy. None of the recipients or donors developed bile leakage. No association between the occurrence of postoperative biliary stricture and donor biliary anatomy type was found (P = 0.527).
Conclusions:
The incidence of biliary stricture in donors or recipients after RLDLT was not related to donor biliary anatomy type. As postoperative complications were similar in whatever type of donor bile duct anatomy, donor ductal anomaly should not be considered a contraindication to donation of right liver lobe. |
Persistent Identifier | http://hdl.handle.net/10722/273402 |
ISSN | 2023 Impact Factor: 3.6 2023 SCImago Journal Rankings: 0.720 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chok, KSH | - |
dc.contributor.author | Fung, JYY | - |
dc.contributor.author | Dai, WC | - |
dc.contributor.author | Sin, SL | - |
dc.contributor.author | Ma, KW | - |
dc.contributor.author | Chan, ACY | - |
dc.contributor.author | Cheung, TT | - |
dc.contributor.author | Lo, CM | - |
dc.date.accessioned | 2019-08-06T09:28:17Z | - |
dc.date.available | 2019-08-06T09:28:17Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Hepatobiliary & Pancreatic Diseases International, 2019, v. 18 n. 4, p. 343-347 | - |
dc.identifier.issn | 1499-3872 | - |
dc.identifier.uri | http://hdl.handle.net/10722/273402 | - |
dc.description.abstract | Background: Data of living-donor liver transplantation (LDLT) suggested that donor ductal anomaly may contribute to postoperative biliary complications in recipients and in donors. This retrospective study aimed to determine if the occurrence of postoperative biliary stricture in donors or recipients in right-lobe LDLT (RLDLT) is related to donor biliary anatomy type. Methods: We analyzed our RLDLT recipients’ clinical data and those of their graft donors. The recipients were divided into 2 groups: with and without postoperative biliary stricture. The 2 groups were compared. The primary endpoints were donor biliary anatomy type and postoperative biliary complication incidence; the secondary endpoints were 1-, 3- and 5-year graft and patient survival rates. Results: Totally 127 patients were included in the study; 25 (19.7%) of them developed biliary anastomotic stricture. In these 25 patients, 16 had type A biliary anatomy, 3 had type B, 2 had type C, 3 had type D, and 1 had type E. In the 127 donors, 96 (75.6%) had type A biliary anatomy, 13 (10.2%) had type B, 6 (4.7%) had type C, 10 (7.9%) had type D, and 2 (1.6%) had type E. Biliary stricture was seen in 2 donors, who had type A biliary anatomy. None of the recipients or donors developed bile leakage. No association between the occurrence of postoperative biliary stricture and donor biliary anatomy type was found (P = 0.527). Conclusions: The incidence of biliary stricture in donors or recipients after RLDLT was not related to donor biliary anatomy type. As postoperative complications were similar in whatever type of donor bile duct anatomy, donor ductal anomaly should not be considered a contraindication to donation of right liver lobe. | - |
dc.language | eng | - |
dc.publisher | Elsevier for the First Affiliated Hospital, Zhejiang University School of Medicine. The Journal's web site is located at http://www.hbpdint.com/ | - |
dc.relation.ispartof | Hepatobiliary & Pancreatic Diseases International | - |
dc.subject | Living donor liver transplantation | - |
dc.subject | Right liver donation | - |
dc.subject | Biliary complications | - |
dc.subject | Cholangiograms | - |
dc.subject | Ductal anomaly | - |
dc.title | Donor ductal anomaly is not a contraindication to right liver lobe donation | - |
dc.type | Article | - |
dc.identifier.email | Chok, KSH: chok6275@hku.hk | - |
dc.identifier.email | Fung, JYY: jfung@hkucc.hku.hk | - |
dc.identifier.email | Dai, WC: daiwc@hku.hk | - |
dc.identifier.email | Chan, ACY: acchan@hku.hk | - |
dc.identifier.email | Cheung, TT: cheung68@hku.hk | - |
dc.identifier.email | Lo, CM: chungmlo@hkucc.hku.hk | - |
dc.identifier.authority | Chok, KSH=rp02110 | - |
dc.identifier.authority | Fung, JYY=rp00518 | - |
dc.identifier.authority | Chan, ACY=rp00310 | - |
dc.identifier.authority | Cheung, TT=rp02129 | - |
dc.identifier.authority | Lo, CM=rp00412 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.hbpd.2019.06.001 | - |
dc.identifier.pmid | 31230961 | - |
dc.identifier.scopus | eid_2-s2.0-85067482014 | - |
dc.identifier.hkuros | 300329 | - |
dc.identifier.volume | 18 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 343 | - |
dc.identifier.epage | 347 | - |
dc.identifier.isi | WOS:000481407500008 | - |
dc.publisher.place | China | - |
dc.identifier.issnl | 2352-9377 | - |