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Conference Paper: Dynamic BOLD Responses of Renal Tissues to interleaved Hypoxia and Hyperoxia in Healthy Rats as Measured by MRI at 7T
Title | Dynamic BOLD Responses of Renal Tissues to interleaved Hypoxia and Hyperoxia in Healthy Rats as Measured by MRI at 7T |
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Authors | |
Issue Date | 2019 |
Publisher | International Society for Magnetic Resonance in Medicine. |
Citation | The 27th Annual Meeting & Exhibition of International Society for Magnetic Resonance in Medicine (ISMRM), Montreal, Canada, 11-16 May 2019 , paper 1221 How to Cite? |
Abstract | Renal oxygen status is tightly correlated with renal (patho)physiology. How the renal oxygen is regulated in response to interleaved hypoxia and hyperoxia has not been well investigated. In this work we utilized dynamic BOLD MRI with temporal resolution of 9 seconds to track the renal tissues oxygen responses in healthy rats, thereafter, characterizing the renal oxygen changes by a mathematic model. In the experiment, significant T2* overshot was observed in outer medulla at the initial stage of re-oxygenation. Significant difference of model parameters compared among renal cortex, outer medulla and inner medulla was observed. |
Description | Oral Presentation - Scientific Session: Preclinical Exploratory Body Methods: Body: Breast, Chest, Abdomen, Pelvis - no. 1221 |
Persistent Identifier | http://hdl.handle.net/10722/278717 |
DC Field | Value | Language |
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dc.contributor.author | Zhao, K | - |
dc.contributor.author | Mei, Y | - |
dc.contributor.author | Yang, G | - |
dc.contributor.author | Wang, Z | - |
dc.contributor.author | Zhou, L | - |
dc.contributor.author | Wu, EX | - |
dc.contributor.author | Feng, Y | - |
dc.date.accessioned | 2019-10-21T02:12:43Z | - |
dc.date.available | 2019-10-21T02:12:43Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | The 27th Annual Meeting & Exhibition of International Society for Magnetic Resonance in Medicine (ISMRM), Montreal, Canada, 11-16 May 2019 , paper 1221 | - |
dc.identifier.uri | http://hdl.handle.net/10722/278717 | - |
dc.description | Oral Presentation - Scientific Session: Preclinical Exploratory Body Methods: Body: Breast, Chest, Abdomen, Pelvis - no. 1221 | - |
dc.description.abstract | Renal oxygen status is tightly correlated with renal (patho)physiology. How the renal oxygen is regulated in response to interleaved hypoxia and hyperoxia has not been well investigated. In this work we utilized dynamic BOLD MRI with temporal resolution of 9 seconds to track the renal tissues oxygen responses in healthy rats, thereafter, characterizing the renal oxygen changes by a mathematic model. In the experiment, significant T2* overshot was observed in outer medulla at the initial stage of re-oxygenation. Significant difference of model parameters compared among renal cortex, outer medulla and inner medulla was observed. | - |
dc.language | eng | - |
dc.publisher | International Society for Magnetic Resonance in Medicine. | - |
dc.relation.ispartof | 2019 Proceedings of International Society for Magnetic Resonance in Medicine (ISMRM) Annual Meeting | - |
dc.title | Dynamic BOLD Responses of Renal Tissues to interleaved Hypoxia and Hyperoxia in Healthy Rats as Measured by MRI at 7T | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Wu, EX: ewu@eee.hku.hk | - |
dc.identifier.authority | Wu, EX=rp00193 | - |
dc.identifier.hkuros | 307700 | - |
dc.identifier.spage | 1221 | - |
dc.identifier.epage | 1221 | - |
dc.publisher.place | United States | - |