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- Publisher Website: 10.1016/j.sempedsurg.2020.150950
- Scopus: eid_2-s2.0-85088937844
- PMID: 32861448
- WOS: WOS:000566777300008
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Article: Biliary atresia: East versus west
Title | Biliary atresia: East versus west |
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Authors | |
Keywords | Biliary atresia Kasai portoenterostomy Liver transplant Biliary atresia splenic malformation syndrome |
Issue Date | 2020 |
Publisher | WB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/sempedsurg |
Citation | Seminars in Pediatric Surgery, 2020, v. 29 n. 4, p. article no. 150950 How to Cite? |
Abstract | Biliary atresia (BA) is a common cause of surgical jaundice during the neonatal period. It is currently considered as a spectrum of diseases with a common final pathology characterized by obliteration of the extrahepatic biliary tract and the absence of normally branching intrahepatic ducts. Though it is a global disease that can be found in all ethnicities there are some clear differences between BA arising in the East and the West. This is likely to be related to different genetic, environmental and cultural factors. BA is more frequently found in Far Eastern infants (both Chinese and Japanese) though the syndromic associations are much less common. Many Eastern countries have national screening programmes not seen in the West possibly due to debate over its cost effectiveness in countries where incidence is low. Kasai portoenterostomy (KPE) is considered as the primary treatment of BA but its outcome still remains unsatisfactory across the region. Given the complexity of BA, it is unlikely that strategic advances could be made by the sole effort of individual countries and we believe that collaboration between the East and West is the way forward. |
Persistent Identifier | http://hdl.handle.net/10722/295283 |
ISSN | 2023 Impact Factor: 1.4 2023 SCImago Journal Rankings: 0.431 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chung, PHY | - |
dc.contributor.author | Zheng, S | - |
dc.contributor.author | Tam, PKH | - |
dc.date.accessioned | 2021-01-11T13:57:55Z | - |
dc.date.available | 2021-01-11T13:57:55Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Seminars in Pediatric Surgery, 2020, v. 29 n. 4, p. article no. 150950 | - |
dc.identifier.issn | 1055-8586 | - |
dc.identifier.uri | http://hdl.handle.net/10722/295283 | - |
dc.description.abstract | Biliary atresia (BA) is a common cause of surgical jaundice during the neonatal period. It is currently considered as a spectrum of diseases with a common final pathology characterized by obliteration of the extrahepatic biliary tract and the absence of normally branching intrahepatic ducts. Though it is a global disease that can be found in all ethnicities there are some clear differences between BA arising in the East and the West. This is likely to be related to different genetic, environmental and cultural factors. BA is more frequently found in Far Eastern infants (both Chinese and Japanese) though the syndromic associations are much less common. Many Eastern countries have national screening programmes not seen in the West possibly due to debate over its cost effectiveness in countries where incidence is low. Kasai portoenterostomy (KPE) is considered as the primary treatment of BA but its outcome still remains unsatisfactory across the region. Given the complexity of BA, it is unlikely that strategic advances could be made by the sole effort of individual countries and we believe that collaboration between the East and West is the way forward. | - |
dc.language | eng | - |
dc.publisher | WB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/sempedsurg | - |
dc.relation.ispartof | Seminars in Pediatric Surgery | - |
dc.subject | Biliary atresia | - |
dc.subject | Kasai portoenterostomy | - |
dc.subject | Liver transplant | - |
dc.subject | Biliary atresia splenic malformation syndrome | - |
dc.title | Biliary atresia: East versus west | - |
dc.type | Article | - |
dc.identifier.email | Chung, PHY: chungphy@hku.hk | - |
dc.identifier.email | Tam, PKH: paultam@hku.hk | - |
dc.identifier.authority | Chung, PHY=rp02002 | - |
dc.identifier.authority | Tam, PKH=rp00060 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.sempedsurg.2020.150950 | - |
dc.identifier.pmid | 32861448 | - |
dc.identifier.scopus | eid_2-s2.0-85088937844 | - |
dc.identifier.hkuros | 320789 | - |
dc.identifier.volume | 29 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | article no. 150950 | - |
dc.identifier.epage | article no. 150950 | - |
dc.identifier.isi | WOS:000566777300008 | - |
dc.publisher.place | United States | - |