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Article: The Liver Tumor Segmentation Benchmark (LiTS)
Title | The Liver Tumor Segmentation Benchmark (LiTS) |
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Authors | Bilic, PChrist, PLi, HBVorontsov, EBen-Cohen, AKaissis, GSzeskin, AJacobs, CMamani, GEHChartrand, GLohofer, FHolch, JWSommer, WHofmann, FHostettler, ALev-Cohain, NDrozdzal, MAmitai, MMVivanti, RSosna, JEzhov, ISekuboyina, ANavarro, FKofler, FPaetzold, JCShit, SHu, XBLipkova, JRempfler, MPiraud, MKirschke, JWiestler, BZhang, ZHHulsemeyer, CBeetz, MEttlinger, FAntonelli, MBae, WBellver, MBi, LChen, HChlebus, GDam, EBDou, QFu, CWGeorgescu, BGiro-I-Nieto, XGruen, FHan, XHeng, PAHesser, JMoltz, JHIgel, CIsensee, FJager, PJia, FCKaluva, KCKhened, MKim, IKim, JHKim, SKohl, SKonopczynski, TKori, AKrishnamurthi, GLi, FLi, HCLi, JBLi, XMLowengrub, JMa, JMaier-Hein, KManinis, KKMeine, HMerhof, DPai, APerslev, MPetersen, JPont-Tuset, JQi, JQi, XJRippel, ORoth, KSarasua, ISchenk, AShen, ZMTorres, JWachinger, CWang, CLWeninger, LWu, JRXu, DGYang, XPYu, SCHYuan, YDYue, MZhang, LPCardoso, JBakas, SBraren, RHeinemann, VPal, CTang, AKadoury, SSoler, Lvan Ginneken, BGreenspan, HJoskowicz, LMenze, B |
Keywords | Benchmark CT Deep learning Liver Liver tumor Segmentation |
Issue Date | 1-Feb-2023 |
Publisher | Elsevier |
Citation | Medical Image Analysis, 2023, v. 84 How to Cite? |
Abstract | In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI) 2017 and the International Conferences on Medical Image Computing and Computer-Assisted Intervention (MICCAI) 2017 and 2018. The image dataset is diverse and contains primary and secondary tumors with varied sizes and appearances with various lesion-to-background levels (hyper-/hypo-dense), created in collaboration with seven hospitals and research institutions. Seventy-five submitted liver and liver tumor segmentation algorithms were trained on a set of 131 computed tomography (CT) volumes and were tested on 70 unseen test images acquired from different patients. We found that not a single algorithm performed best for both liver and liver tumors in the three events. The best liver segmentation algorithm achieved a Dice score of 0.963, whereas, for tumor segmentation, the best algorithms achieved Dices scores of 0.674 (ISBI 2017), 0.702 (MICCAI 2017), and 0.739 (MICCAI 2018). Retrospectively, we performed additional analysis on liver tumor detection and revealed that not all top-performing segmentation algorithms worked well for tumor detection. The best liver tumor detection method achieved a lesion-wise recall of 0.458 (ISBI 2017), 0.515 (MICCAI 2017), and 0.554 (MICCAI 2018), indicating the need for further research. LiTS remains an active benchmark and resource for research, e.g., contributing the liver-related segmentation tasks in http://medicaldecathlon.com/. In addition, both data and online evaluation are accessible via https://competitions.codalab.org/competitions/17094. |
Persistent Identifier | http://hdl.handle.net/10722/333924 |
ISSN | 2023 Impact Factor: 10.7 2023 SCImago Journal Rankings: 4.112 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bilic, P | - |
dc.contributor.author | Christ, P | - |
dc.contributor.author | Li, HB | - |
dc.contributor.author | Vorontsov, E | - |
dc.contributor.author | Ben-Cohen, A | - |
dc.contributor.author | Kaissis, G | - |
dc.contributor.author | Szeskin, A | - |
dc.contributor.author | Jacobs, C | - |
dc.contributor.author | Mamani, GEH | - |
dc.contributor.author | Chartrand, G | - |
dc.contributor.author | Lohofer, F | - |
dc.contributor.author | Holch, JW | - |
dc.contributor.author | Sommer, W | - |
dc.contributor.author | Hofmann, F | - |
dc.contributor.author | Hostettler, A | - |
dc.contributor.author | Lev-Cohain, N | - |
dc.contributor.author | Drozdzal, M | - |
dc.contributor.author | Amitai, MM | - |
dc.contributor.author | Vivanti, R | - |
dc.contributor.author | Sosna, J | - |
dc.contributor.author | Ezhov, I | - |
dc.contributor.author | Sekuboyina, A | - |
dc.contributor.author | Navarro, F | - |
dc.contributor.author | Kofler, F | - |
dc.contributor.author | Paetzold, JC | - |
dc.contributor.author | Shit, S | - |
dc.contributor.author | Hu, XB | - |
dc.contributor.author | Lipkova, J | - |
dc.contributor.author | Rempfler, M | - |
dc.contributor.author | Piraud, M | - |
dc.contributor.author | Kirschke, J | - |
dc.contributor.author | Wiestler, B | - |
dc.contributor.author | Zhang, ZH | - |
dc.contributor.author | Hulsemeyer, C | - |
dc.contributor.author | Beetz, M | - |
dc.contributor.author | Ettlinger, F | - |
dc.contributor.author | Antonelli, M | - |
dc.contributor.author | Bae, W | - |
dc.contributor.author | Bellver, M | - |
dc.contributor.author | Bi, L | - |
dc.contributor.author | Chen, H | - |
dc.contributor.author | Chlebus, G | - |
dc.contributor.author | Dam, EB | - |
dc.contributor.author | Dou, Q | - |
dc.contributor.author | Fu, CW | - |
dc.contributor.author | Georgescu, B | - |
dc.contributor.author | Giro-I-Nieto, X | - |
dc.contributor.author | Gruen, F | - |
dc.contributor.author | Han, X | - |
dc.contributor.author | Heng, PA | - |
dc.contributor.author | Hesser, J | - |
dc.contributor.author | Moltz, JH | - |
dc.contributor.author | Igel, C | - |
dc.contributor.author | Isensee, F | - |
dc.contributor.author | Jager, P | - |
dc.contributor.author | Jia, FC | - |
dc.contributor.author | Kaluva, KC | - |
dc.contributor.author | Khened, M | - |
dc.contributor.author | Kim, I | - |
dc.contributor.author | Kim, JH | - |
dc.contributor.author | Kim, S | - |
dc.contributor.author | Kohl, S | - |
dc.contributor.author | Konopczynski, T | - |
dc.contributor.author | Kori, A | - |
dc.contributor.author | Krishnamurthi, G | - |
dc.contributor.author | Li, F | - |
dc.contributor.author | Li, HC | - |
dc.contributor.author | Li, JB | - |
dc.contributor.author | Li, XM | - |
dc.contributor.author | Lowengrub, J | - |
dc.contributor.author | Ma, J | - |
dc.contributor.author | Maier-Hein, K | - |
dc.contributor.author | Maninis, KK | - |
dc.contributor.author | Meine, H | - |
dc.contributor.author | Merhof, D | - |
dc.contributor.author | Pai, A | - |
dc.contributor.author | Perslev, M | - |
dc.contributor.author | Petersen, J | - |
dc.contributor.author | Pont-Tuset, J | - |
dc.contributor.author | Qi, J | - |
dc.contributor.author | Qi, XJ | - |
dc.contributor.author | Rippel, O | - |
dc.contributor.author | Roth, K | - |
dc.contributor.author | Sarasua, I | - |
dc.contributor.author | Schenk, A | - |
dc.contributor.author | Shen, ZM | - |
dc.contributor.author | Torres, J | - |
dc.contributor.author | Wachinger, C | - |
dc.contributor.author | Wang, CL | - |
dc.contributor.author | Weninger, L | - |
dc.contributor.author | Wu, JR | - |
dc.contributor.author | Xu, DG | - |
dc.contributor.author | Yang, XP | - |
dc.contributor.author | Yu, SCH | - |
dc.contributor.author | Yuan, YD | - |
dc.contributor.author | Yue, M | - |
dc.contributor.author | Zhang, LP | - |
dc.contributor.author | Cardoso, J | - |
dc.contributor.author | Bakas, S | - |
dc.contributor.author | Braren, R | - |
dc.contributor.author | Heinemann, V | - |
dc.contributor.author | Pal, C | - |
dc.contributor.author | Tang, A | - |
dc.contributor.author | Kadoury, S | - |
dc.contributor.author | Soler, L | - |
dc.contributor.author | van Ginneken, B | - |
dc.contributor.author | Greenspan, H | - |
dc.contributor.author | Joskowicz, L | - |
dc.contributor.author | Menze, B | - |
dc.date.accessioned | 2023-10-10T03:14:26Z | - |
dc.date.available | 2023-10-10T03:14:26Z | - |
dc.date.issued | 2023-02-01 | - |
dc.identifier.citation | Medical Image Analysis, 2023, v. 84 | - |
dc.identifier.issn | 1361-8415 | - |
dc.identifier.uri | http://hdl.handle.net/10722/333924 | - |
dc.description.abstract | <p>In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/biomedical-imaging" title="Learn more about Biomedical Imaging from ScienceDirect's AI-generated Topic Pages">Biomedical Imaging</a> (ISBI) 2017 and the International Conferences on Medical Image Computing and Computer-Assisted Intervention (MICCAI) 2017 and 2018. The image dataset is diverse and contains primary and secondary tumors with varied sizes and appearances with various lesion-to-background levels (hyper-/hypo-dense), created in collaboration with seven <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/hospital" title="Learn more about hospitals from ScienceDirect's AI-generated Topic Pages">hospitals</a> and research institutions. Seventy-five submitted liver and liver tumor segmentation algorithms were trained on a set of 131 computed tomography (CT) volumes and were tested on 70 unseen test images acquired from different <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/patient" title="Learn more about patients from ScienceDirect's AI-generated Topic Pages">patients</a>. We found that not a single algorithm performed best for both liver and liver tumors in the three events. The best <a href="https://www.sciencedirect.com/topics/computer-science/liver-segmentation" title="Learn more about liver segmentation from ScienceDirect's AI-generated Topic Pages">liver segmentation</a> algorithm achieved a Dice score of 0.963, whereas, for tumor segmentation, the best algorithms achieved Dices scores of 0.674 (ISBI 2017), 0.702 (MICCAI 2017), and 0.739 (MICCAI 2018). Retrospectively, we performed additional analysis on liver <a href="https://www.sciencedirect.com/topics/computer-science/tumor-detection" title="Learn more about tumor detection from ScienceDirect's AI-generated Topic Pages">tumor detection</a> and revealed that not all top-performing segmentation algorithms worked well for tumor detection. The best liver tumor detection method achieved a lesion-wise recall of 0.458 (ISBI 2017), 0.515 (MICCAI 2017), and 0.554 (MICCAI 2018), indicating the need for further research. LiTS remains an active benchmark and resource for research, e.g., contributing the liver-related <a href="https://www.sciencedirect.com/topics/computer-science/segmentation-task" title="Learn more about segmentation tasks from ScienceDirect's AI-generated Topic Pages">segmentation tasks</a> in <a href="http://medicaldecathlon.com/">http://medicaldecathlon.com/</a>. In addition, both data and online evaluation are accessible via <a href="https://competitions.codalab.org/competitions/17094">https://competitions.codalab.org/competitions/17094</a>.</p> | - |
dc.language | eng | - |
dc.publisher | Elsevier | - |
dc.relation.ispartof | Medical Image Analysis | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Benchmark | - |
dc.subject | CT | - |
dc.subject | Deep learning | - |
dc.subject | Liver | - |
dc.subject | Liver tumor | - |
dc.subject | Segmentation | - |
dc.title | The Liver Tumor Segmentation Benchmark (LiTS) | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.media.2022.102680 | - |
dc.identifier.scopus | eid_2-s2.0-85143743210 | - |
dc.identifier.volume | 84 | - |
dc.identifier.isi | WOS:000928244200004 | - |
dc.identifier.issnl | 1361-8415 | - |