425. VENOUS THROMBOEMBOLISM AFTER OEOSPHAGECTOMY—CHEMICAL THROMBOPROPHYLAXIS MIGHT NOT BE NECESSARY IN ALL ASIAN POPULATION

Abstract

<p>Methods<br>A retrospective review of a prospectively maintained database into the rate of VTE in all patients undergoing oesophagectomy for cancer. VTE is defined as clinically significant pulmonary embolism or deep vein thrombosis. Statistical analysis performed using R. Deidentified patient demographics, tumour characteristic, treatment details, short term and long-term outcome were analysed.</p><p>Results<br>353 oesophagectomies were performed Between 2013–2024. The rate of VTE in our centre where routine chemoprophylaxis is not prescribed is 3.68%. There is no significant difference compared to international published data on VTE rates. (p = 0.378) There were also no significant association between sex, age or smoking status and VTE rate. However, there was statistical significance when the length of operation was analyzed against VTE rate (p = 0.032) with 12% (n = 66) of patients undergoing surgery >10 hrs suffering from VTE and 1.7% (n = 281) did not. No patient who had an operation under 6 hours had VTE.</p><p>Conclusion<br>Routine VTE chemoprophylaxis might not be necessary in all patients undergoing oesophagectomy for cancer. However patients undergoing longer operations should be considered for VTE chemoprophylaxis. This supports the notion of personalised cancer care where there is no ‘one size fits all’ solution to cancer management.</p>