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  Patent History
  • Application
    US 09/011146 2001-11-09
  • Publication
    US 20030104511 2003-06-05
  • Granted
    US 6723529 2004-04-20
  Patent Family
Supplementary

granted patent: Methods For The Identification Of Inhibitors Of Alpha-Aminoadipate Reductase As Antibiotics

TitleMethods For The Identification Of Inhibitors Of Alpha-Aminoadipate Reductase As Antibiotics
Granted PatentUS 6723529
Granted Date2004-04-20
Priority Date2001-11-09 US 09/011146
Inventors
Tanzer, TTanzer, MMHamer, LAdachi, KDeZwaan, TLo, CSCMontenegro-Chamorro, MVFrank, SDarveaux, BMahanty, SHeiniger, RSkalchunes, APan, HTarpey, RShuster, J
Issue Date2004
Citation
US Patent 6723529. Washington, DC: US Patent and Trademark Office (USPTO), 2004 How to Cite?
AbstractThe Present Inventors Have Discovered That Alpha-Aminoadipate Reductase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Alpha-Aminoadipate Reductase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Alpha-Aminoadipate Reductase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit Alpha-Aminoadipate Reductase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.
Persistent Identifierhttp://hdl.handle.net/10722/45686
References

 

DC FieldValueLanguage
dc.date.accessioned2007-10-30T06:32:39Z-
dc.date.available2007-10-30T06:32:39Z-
dc.date.issued2004-
dc.identifier.citationUS Patent 6723529. Washington, DC: US Patent and Trademark Office (USPTO), 2004en_HK
dc.identifier.urihttp://hdl.handle.net/10722/45686-
dc.description.abstractThe Present Inventors Have Discovered That Alpha-Aminoadipate Reductase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Alpha-Aminoadipate Reductase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Alpha-Aminoadipate Reductase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit Alpha-Aminoadipate Reductase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.en_HK
dc.format.extent3233115 bytes-
dc.format.extent2788 bytes-
dc.format.mimetypeapplication/pdf-
dc.format.mimetypetext/plain-
dc.languageengen_HK
dc.titleMethods For The Identification Of Inhibitors Of Alpha-Aminoadipate Reductase As Antibioticsen_HK
dc.typePatenten_HK
dc.description.naturepublished_or_final_version-
dc.contributor.inventorTanzer, Ten_HK
dc.contributor.inventorTanzer, MMen_HK
dc.contributor.inventorHamer, Len_HK
dc.contributor.inventorAdachi, Ken_HK
dc.contributor.inventorDeZwaan, Ten_HK
dc.contributor.inventorLo, CSCen_HK
dc.contributor.inventorMontenegro-Chamorro, MVen_HK
dc.contributor.inventorFrank, Sen_HK
dc.contributor.inventorDarveaux, Ben_HK
dc.contributor.inventorMahanty, Sen_HK
dc.contributor.inventorHeiniger, Ren_HK
dc.contributor.inventorSkalchunes, Aen_HK
dc.contributor.inventorPan, Hen_HK
dc.contributor.inventorTarpey, Ren_HK
dc.contributor.inventorShuster, Jen_HK
patents.identifier.applicationUS 09/011146en_HK
patents.identifier.grantedUS 6723529en_HK
patents.description.assigneeParadigm Genetics Inc [Us]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2003-06-05en_HK
patents.date.granted2004-04-20en_HK
dc.relation.referencesWO 0000643 (A2) 2000-01-06en_HK
dc.relation.referencesWO 0000643 (A3) 2000-03-23en_HK
dc.relation.referencesUS 4920109 (A) 1990-04-24en_HK
dc.relation.referencesUS 4920111 (A) 1990-04-24en_HK
dc.relation.referencesUS 4920112 (A) 1990-04-24en_HK
dc.relation.referencesUS 4920113 (A) 1990-04-24en_HK
dc.relation.referencesUS 4921844 (A) 1990-05-01en_HK
dc.relation.referencesUS 5976848 (A) 1999-11-02en_HK
dc.relation.referencesUS 6074830 (A) 2000-06-13en_HK
patents.date.application2001-11-09en_HK
patents.date.priority2001-11-09 US 09/011146en_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 20030104511en_HK
patents.relation.familyAU 2002365038 (A8) 2003-06-10en_HK
patents.relation.familyCA 2469772 (A1) 2003-06-05en_HK
patents.relation.familyEP 1481080 (A2) 2004-12-01en_HK
patents.relation.familyJP 2005510230 (A) 2005-04-21en_HK
patents.relation.familyUS 2003180829 (A1) 2003-09-25en_HK
patents.relation.familyUS 6632631 (B1) 2003-10-14en_HK
patents.relation.familyUS 2003104511 (A1) 2003-06-05en_HK
patents.relation.familyUS 6723529 (B2) 2004-04-20en_HK
patents.relation.familyWO 03046130 (A2) 2003-06-05en_HK
patents.description.kindB2en_HK
patents.typePatent_granteden_HK

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