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Article: Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer

TitleAntioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer
Authors
KeywordsABTS
Anticancer
Antioxidant activity
Flavonoids
Free radical
Phenolic acids
Phenolic compounds
Quinones
Tannins
Traditional Chinese Medicines
Issue Date2004
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/lifescie
Citation
Life Sciences, 2004, v. 74 n. 17, p. 2157-2184 How to Cite?
AbstractCancer prevention and treatment using traditional Chinese medicines have attracted increasing interest. This study characterizes antioxidant activity and phenolic compounds of traditional Chinese medicinal plants associated with anticancer, comprising 112 species from 50 plant families. The improved ABTS •+ method was used to systematically assess the total antioxidant capacity (Trolox equivalent antioxidant capacity, TEAC) of the medicinal extracts. The TEAC values and total phenolic content for methanolic extracts of herbs ranged from 46.7 to 17,323 μmol Trolox equivalent/100 g dry weight (DW), and from 0.22 to 50.3 g of gallic acid equivalent/100 g DW, respectively. A positive, significant linear relationship between antioxidant activity and total phenolic content (all R 2 values≥0.95) showed that phenolic compounds were the dominant antioxidant components in the tested medicinal herbs. Major types of phenolic compounds from most of the tested herbs were preliminarily identified and analyzed, and mainly included phenolic acids, flavonoids, tannins, coumarins, lignans, quinones, stilbenes, and curcuminoids. These medicinal herbs exhibited far stronger antioxidant activity and contained significantly higher levels of phenolics than common vegetables and fruits. Traditional Chinese medicinal plants associated with anticancer might be potential sources of potent natural antioxidants and beneficial chemopreventive agents. © 2003 Published by Elsevier Inc.
Persistent Identifierhttp://hdl.handle.net/10722/68501
ISSN
2023 Impact Factor: 5.2
2023 SCImago Journal Rankings: 1.257
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCai, Yen_HK
dc.contributor.authorLuo, Qen_HK
dc.contributor.authorSun, Men_HK
dc.contributor.authorCorke, Hen_HK
dc.date.accessioned2010-09-06T06:05:10Z-
dc.date.available2010-09-06T06:05:10Z-
dc.date.issued2004en_HK
dc.identifier.citationLife Sciences, 2004, v. 74 n. 17, p. 2157-2184en_HK
dc.identifier.issn0024-3205en_HK
dc.identifier.urihttp://hdl.handle.net/10722/68501-
dc.description.abstractCancer prevention and treatment using traditional Chinese medicines have attracted increasing interest. This study characterizes antioxidant activity and phenolic compounds of traditional Chinese medicinal plants associated with anticancer, comprising 112 species from 50 plant families. The improved ABTS •+ method was used to systematically assess the total antioxidant capacity (Trolox equivalent antioxidant capacity, TEAC) of the medicinal extracts. The TEAC values and total phenolic content for methanolic extracts of herbs ranged from 46.7 to 17,323 μmol Trolox equivalent/100 g dry weight (DW), and from 0.22 to 50.3 g of gallic acid equivalent/100 g DW, respectively. A positive, significant linear relationship between antioxidant activity and total phenolic content (all R 2 values≥0.95) showed that phenolic compounds were the dominant antioxidant components in the tested medicinal herbs. Major types of phenolic compounds from most of the tested herbs were preliminarily identified and analyzed, and mainly included phenolic acids, flavonoids, tannins, coumarins, lignans, quinones, stilbenes, and curcuminoids. These medicinal herbs exhibited far stronger antioxidant activity and contained significantly higher levels of phenolics than common vegetables and fruits. Traditional Chinese medicinal plants associated with anticancer might be potential sources of potent natural antioxidants and beneficial chemopreventive agents. © 2003 Published by Elsevier Inc.en_HK
dc.languageengen_HK
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/lifescieen_HK
dc.relation.ispartofLife Sciencesen_HK
dc.subjectABTSen_HK
dc.subjectAnticanceren_HK
dc.subjectAntioxidant activityen_HK
dc.subjectFlavonoidsen_HK
dc.subjectFree radicalen_HK
dc.subjectPhenolic acidsen_HK
dc.subjectPhenolic compoundsen_HK
dc.subjectQuinonesen_HK
dc.subjectTanninsen_HK
dc.subjectTraditional Chinese Medicinesen_HK
dc.subject.meshAntineoplastic Agents, Phytogenic-
dc.subject.meshAntioxidants - analysis-
dc.subject.meshDrugs, Chinese Herbal - chemistry-
dc.subject.meshPhenols - analysis - chemistry-
dc.subject.meshPlant Extracts - chemistry-
dc.titleAntioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticanceren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0024-3205&volume=74 &issue=17&spage=2157&epage=2184&date=2004&atitle=Antioxidant+activity+and+phenolic+compounds+of+112+traditional+Chinese+medicinal+plants+associated+with+anticanceren_HK
dc.identifier.emailCai, Y: yzcai@hkucc.hku.hken_HK
dc.identifier.emailSun, M: meisun@hkucc.hku.hken_HK
dc.identifier.emailCorke, H: harold@hku.hken_HK
dc.identifier.authorityCai, Y=rp00661en_HK
dc.identifier.authoritySun, M=rp00779en_HK
dc.identifier.authorityCorke, H=rp00688en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.lfs.2003.09.047en_HK
dc.identifier.pmid14969719-
dc.identifier.scopuseid_2-s2.0-1142297395en_HK
dc.identifier.hkuros91093en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-1142297395&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume74en_HK
dc.identifier.issue17en_HK
dc.identifier.spage2157en_HK
dc.identifier.epage2184en_HK
dc.identifier.isiWOS:000189221100006-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridCai, Y=8684149300en_HK
dc.identifier.scopusauthoridLuo, Q=35311306700en_HK
dc.identifier.scopusauthoridSun, M=7403181447en_HK
dc.identifier.scopusauthoridCorke, H=7007102942en_HK
dc.identifier.issnl0024-3205-

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