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- Publisher Website: 10.1016/S0016-5107(97)70004-X
- Scopus: eid_2-s2.0-0031445628
- PMID: 9434216
- WOS: WOS:000071094900004
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Article: A prospective comparison of locally made rapid urease test and histology for the diagnosis of Helicobacter pylori infection
Title | A prospective comparison of locally made rapid urease test and histology for the diagnosis of Helicobacter pylori infection |
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Authors | |
Issue Date | 1997 |
Publisher | Mosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/gie |
Citation | Gastrointestinal Endoscopy, 1997, v. 46 n. 6, p. 503-506 How to Cite? |
Abstract | Background: A number of noncommercial preparations of urease test have been described. The present prospective study evaluated the accuracy of one such preparation for the diagnosis of Helicobacter pylori infection. Methods: From February 1996 to November 1996, all patients undergoing elective upper endoscopy in a single endoscopy facility were included. Three antral biopsy specimens were taken. Two specimens were subjected to histologic examination, and one specimen was placed into a 'locally made rapid urease test' (LRUT). Results of histologic examinations were taken as standards for comparison. The final result of LRUT was obtained on scrutiny of color changes at 4 hours after the start of the test. Results: Two thousand three hundred sixteen patients (male/female = 1.5:1) with a mean age of 56.7 ± 0.4 years were included. Five hundred sixty-two patients (24.3%) had a history of eradication treatment for H. pylori. Nine hundred fifty-three patients (41.1%) were found to be positive for H. pylori on histologic examination. In patients in whom a history of eradication therapy was absent, the sensitivity, specificity, and positive and negative predictive values of the LRUT were 92.8%, 97.6%, 97.5%, and 93.0%, respectively. In patients with a history of eradication treatment, the corresponding figures were 76.1%, 99.6%, 96.2%, and 96.9%. Conclusions: The locally made rapid urease test provides a simple, safe, rapid, inexpensive, and accurate test for the diagnosis of H. pylori infection. |
Persistent Identifier | http://hdl.handle.net/10722/84264 |
ISSN | 2023 Impact Factor: 6.7 2023 SCImago Journal Rankings: 1.749 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chu, KM | en_HK |
dc.contributor.author | Poon, R | en_HK |
dc.contributor.author | Tuen, HH | en_HK |
dc.contributor.author | Law, SYK | en_HK |
dc.contributor.author | Branicki, FJ | en_HK |
dc.contributor.author | Wong, J | en_HK |
dc.date.accessioned | 2010-09-06T08:50:54Z | - |
dc.date.available | 2010-09-06T08:50:54Z | - |
dc.date.issued | 1997 | en_HK |
dc.identifier.citation | Gastrointestinal Endoscopy, 1997, v. 46 n. 6, p. 503-506 | en_HK |
dc.identifier.issn | 0016-5107 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/84264 | - |
dc.description.abstract | Background: A number of noncommercial preparations of urease test have been described. The present prospective study evaluated the accuracy of one such preparation for the diagnosis of Helicobacter pylori infection. Methods: From February 1996 to November 1996, all patients undergoing elective upper endoscopy in a single endoscopy facility were included. Three antral biopsy specimens were taken. Two specimens were subjected to histologic examination, and one specimen was placed into a 'locally made rapid urease test' (LRUT). Results of histologic examinations were taken as standards for comparison. The final result of LRUT was obtained on scrutiny of color changes at 4 hours after the start of the test. Results: Two thousand three hundred sixteen patients (male/female = 1.5:1) with a mean age of 56.7 ± 0.4 years were included. Five hundred sixty-two patients (24.3%) had a history of eradication treatment for H. pylori. Nine hundred fifty-three patients (41.1%) were found to be positive for H. pylori on histologic examination. In patients in whom a history of eradication therapy was absent, the sensitivity, specificity, and positive and negative predictive values of the LRUT were 92.8%, 97.6%, 97.5%, and 93.0%, respectively. In patients with a history of eradication treatment, the corresponding figures were 76.1%, 99.6%, 96.2%, and 96.9%. Conclusions: The locally made rapid urease test provides a simple, safe, rapid, inexpensive, and accurate test for the diagnosis of H. pylori infection. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Mosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/gie | en_HK |
dc.relation.ispartof | Gastrointestinal Endoscopy | en_HK |
dc.rights | Gastrointestinal Endoscopy. Copyright © Mosby, Inc. | en_HK |
dc.title | A prospective comparison of locally made rapid urease test and histology for the diagnosis of Helicobacter pylori infection | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0016-5107&volume=46&spage=503&epage=506&date=1997&atitle=A+prospective+comparison+of+locally+made+rapid+urease+test+and+histology+for+the+diagnosis+of+helicobacter+pylori+infection | en_HK |
dc.identifier.email | Chu, KM: chukm@hkucc.hku.hk | en_HK |
dc.identifier.email | Poon, R: poontp@hku.hk | en_HK |
dc.identifier.email | Law, SYK: slaw@hku.hk | en_HK |
dc.identifier.email | Wong, J: jwong@hkucc.hku.hk | en_HK |
dc.identifier.authority | Chu, KM=rp00435 | en_HK |
dc.identifier.authority | Poon, R=rp00446 | en_HK |
dc.identifier.authority | Law, SYK=rp00437 | en_HK |
dc.identifier.authority | Wong, J=rp00322 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/S0016-5107(97)70004-X | - |
dc.identifier.pmid | 9434216 | - |
dc.identifier.scopus | eid_2-s2.0-0031445628 | en_HK |
dc.identifier.hkuros | 29943 | en_HK |
dc.identifier.volume | 46 | en_HK |
dc.identifier.issue | 6 | en_HK |
dc.identifier.spage | 503 | en_HK |
dc.identifier.epage | 506 | en_HK |
dc.identifier.isi | WOS:000071094900004 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Chu, KM=7402453538 | en_HK |
dc.identifier.scopusauthorid | Poon, R=7103097223 | en_HK |
dc.identifier.scopusauthorid | Tuen, HH=6602991320 | en_HK |
dc.identifier.scopusauthorid | Law, SYK=7202241293 | en_HK |
dc.identifier.scopusauthorid | Branicki, FJ=7003617514 | en_HK |
dc.identifier.scopusauthorid | Wong, J=8049324500 | en_HK |
dc.identifier.issnl | 0016-5107 | - |