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Conference Paper: Lactic-acid-induced ATP release from rat skeletal muscular L6 cells is mediated by cystic fibrosis transmembrane conductance regulator (CFTR) channels
| Title | Lactic-acid-induced ATP release from rat skeletal muscular L6 cells is mediated by cystic fibrosis transmembrane conductance regulator (CFTR) channels |
|---|---|
| Authors | |
| Keywords | Cardiovascular disease |
| Issue Date | 2008 |
| Publisher | Hong Kong College of Cardiology. The Journal's web site is located at http://www.hkcchk.com/journals.php#3 |
| Citation | The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine (ICSM 2008), Faculty of Medicine, the University of Hong Kong, Hong Kong, China, 13-14 December 2008. In Journal of the Hong Kong College of Cardiology, 2008, v. 16 n. 2, p. 65, abstract no. P8 How to Cite? |
| Abstract | BACKGROUND AND OBJECTIVE: We had previously shown that lactic-acidinfusion increased the interstitial ATP concentration of perfused rat skeletal muscle in-vivo, which could be inhibited by CFTRinh-172, a specific inhibitor of CFTR. A stable rat skeletal muscular L6 cell line was used in this study to confirm that skeletal muscle cells (rather than nerve or vascular cells) were responsible for the acidosis-induced ATP release; the role of CFTR in mediating the ATP efflux during lactic acid incubation was confirmed using … |
| Description | This journal issue is proceedings of ICSM 2008 Poster Session |
| Persistent Identifier | http://hdl.handle.net/10722/140566 |
| ISSN | 2020 SCImago Journal Rankings: 0.105 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Tu, J | en_US |
| dc.contributor.author | Ballard, HJ | en_US |
| dc.date.accessioned | 2011-09-23T06:14:27Z | - |
| dc.date.available | 2011-09-23T06:14:27Z | - |
| dc.date.issued | 2008 | en_US |
| dc.identifier.citation | The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine (ICSM 2008), Faculty of Medicine, the University of Hong Kong, Hong Kong, China, 13-14 December 2008. In Journal of the Hong Kong College of Cardiology, 2008, v. 16 n. 2, p. 65, abstract no. P8 | en_US |
| dc.identifier.issn | 1027-7811 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10722/140566 | - |
| dc.description | This journal issue is proceedings of ICSM 2008 | - |
| dc.description | Poster Session | - |
| dc.description.abstract | BACKGROUND AND OBJECTIVE: We had previously shown that lactic-acidinfusion increased the interstitial ATP concentration of perfused rat skeletal muscle in-vivo, which could be inhibited by CFTRinh-172, a specific inhibitor of CFTR. A stable rat skeletal muscular L6 cell line was used in this study to confirm that skeletal muscle cells (rather than nerve or vascular cells) were responsible for the acidosis-induced ATP release; the role of CFTR in mediating the ATP efflux during lactic acid incubation was confirmed using … | - |
| dc.language | eng | en_US |
| dc.publisher | Hong Kong College of Cardiology. The Journal's web site is located at http://www.hkcchk.com/journals.php#3 | en_US |
| dc.relation.ispartof | Journal of the Hong Kong College of Cardiology | en_US |
| dc.subject | Cardiovascular disease | - |
| dc.title | Lactic-acid-induced ATP release from rat skeletal muscular L6 cells is mediated by cystic fibrosis transmembrane conductance regulator (CFTR) channels | en_US |
| dc.type | Conference_Paper | en_US |
| dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1027-7811&volume=16&issue=2&spage=65&epage=&date=2008&atitle=Lactic-acid-induced+ATP+release+from+rat+skeletal+muscular+L6+cells+is+mediated+by+cystic+fibrosis+transmembrane+conductance+regulator+(CFTR)+channels | en_US |
| dc.identifier.email | Ballard, HJ: ballard@hkucc.hku.hk | en_US |
| dc.identifier.authority | Ballard, HJ=rp00367 | en_US |
| dc.description.nature | link_to_OA_fulltext | - |
| dc.identifier.hkuros | 196066 | en_US |
| dc.identifier.volume | 16 | en_US |
| dc.identifier.issue | 2 | - |
| dc.identifier.spage | 65, abstract no. P8 | en_US |
| dc.identifier.epage | 65, abstract no. P8 | en_US |
| dc.publisher.place | Hong Kong | - |
| dc.description.other | The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine (ICSM), Faculty of Medicine, the University of Hong Kong, Hong Kong, China, 13-14 December 2008. In Journal of the Hong Kong College of Cardiology, 2008, v. 16 n. 2, p. 65, abstract no. P8 | - |
| dc.identifier.issnl | 1027-7811 | - |