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Conference Paper: Analysis of long-range chromatin interaction and how transcription factors are involved to regulate gene expression
| Title | Analysis of long-range chromatin interaction and how transcription factors are involved to regulate gene expression |
|---|---|
| Authors | |
| Issue Date | 2014 |
| Citation | The 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 23, poster no. 21 How to Cite? |
| Abstract | DNA sequences in nucleus are highly condensed to form chromatins. Due to the compact three-dimensional conformation of chromatin, DNA sequences with large genomic distance are possible to be physically close. The spatial proximity between distant genomic regions is informative in explaining how distant cis-regulatory elements affect gene expression. With the advance of biological technologies we are able to detect the three-dimensional structure of chromosomes and long-range interaction of high resolution. Here we process human Hi-C data to draw a whole-genome interaction map with ... |
| Description | Poster presentation - Theme 1: Cell biology |
| Persistent Identifier | http://hdl.handle.net/10722/203851 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Wang, Y | en_US |
| dc.contributor.author | Wang, J | en_US |
| dc.date.accessioned | 2014-09-19T16:42:19Z | - |
| dc.date.available | 2014-09-19T16:42:19Z | - |
| dc.date.issued | 2014 | en_US |
| dc.identifier.citation | The 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Hong Kong, 14 June 2014. In Program Booklet, 2014, p. 23, poster no. 21 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10722/203851 | - |
| dc.description | Poster presentation - Theme 1: Cell biology | - |
| dc.description.abstract | DNA sequences in nucleus are highly condensed to form chromatins. Due to the compact three-dimensional conformation of chromatin, DNA sequences with large genomic distance are possible to be physically close. The spatial proximity between distant genomic regions is informative in explaining how distant cis-regulatory elements affect gene expression. With the advance of biological technologies we are able to detect the three-dimensional structure of chromosomes and long-range interaction of high resolution. Here we process human Hi-C data to draw a whole-genome interaction map with ... | - |
| dc.language | eng | en_US |
| dc.relation.ispartof | Hong Kong Inter-University Biochemistry Postgraduate Symposium | en_US |
| dc.title | Analysis of long-range chromatin interaction and how transcription factors are involved to regulate gene expression | en_US |
| dc.type | Conference_Paper | en_US |
| dc.identifier.email | Wang, J: junwen@hku.hk | en_US |
| dc.identifier.authority | Wang, J=rp00280 | en_US |
| dc.description.nature | postprint | - |
| dc.identifier.hkuros | 240328 | en_US |
| dc.identifier.spage | 23, poster no. 21 | - |
| dc.identifier.epage | 23, poster no. 21 | - |