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Conference Paper: Rutin increases the efficacy of temozolomide in glioblastoma via autophagy inhibition

TitleRutin increases the efficacy of temozolomide in glioblastoma via autophagy inhibition
Authors
Zhang, PLeung, GKK
Issue Date2015
Citation
The 2015 Conjoint Annual Scientific Meeting (ASM) of the Hong Kong Neurosurgical Society (HKNS), Hong Kong, 20-21 November 2015. How to Cite?
AbstractThe chemotherapeutic agent temozolomide (TMZ) is commonly used in glioblastoma (GBM) therapy, but patients usually have a poor prognosis. Rutin, a citrus flavonoid ecglycoside found in edible plants, has neuroprotection and anticancer activities. This study aims to investigate the efficacy of rutin in combination with temozolomide and the underlying mechanisms. In vitro viability assay demonstrated that rutin alone had generally low cytotoxic effect, but it was able to ...
DescriptionConference Theme: Brain Attack: A New Era
Posters: no. P-15
Persistent Identifierhttp://hdl.handle.net/10722/222053

 

DC FieldValueLanguage
dc.contributor.authorZhang, P-
dc.contributor.authorLeung, GKK-
dc.date.accessioned2015-12-21T05:54:02Z-
dc.date.available2015-12-21T05:54:02Z-
dc.date.issued2015-
dc.identifier.citationThe 2015 Conjoint Annual Scientific Meeting (ASM) of the Hong Kong Neurosurgical Society (HKNS), Hong Kong, 20-21 November 2015.-
dc.identifier.urihttp://hdl.handle.net/10722/222053-
dc.descriptionConference Theme: Brain Attack: A New Era-
dc.descriptionPosters: no. P-15-
dc.description.abstractThe chemotherapeutic agent temozolomide (TMZ) is commonly used in glioblastoma (GBM) therapy, but patients usually have a poor prognosis. Rutin, a citrus flavonoid ecglycoside found in edible plants, has neuroprotection and anticancer activities. This study aims to investigate the efficacy of rutin in combination with temozolomide and the underlying mechanisms. In vitro viability assay demonstrated that rutin alone had generally low cytotoxic effect, but it was able to ...-
dc.languageeng-
dc.relation.ispartofHKNS Conjoint Annual Scientific Meeting, ASM 2015-
dc.titleRutin increases the efficacy of temozolomide in glioblastoma via autophagy inhibition-
dc.typeConference_Paper-
dc.identifier.emailZhang, P: pingder@hku.hk-
dc.identifier.emailLeung, GKK: gkkleung@hku.hk-
dc.identifier.authorityLeung, GKK=rp00522-
dc.description.naturepostprint-
dc.identifier.hkuros256336-

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