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Conference Paper: Rapid prototyping aptamer-enabled malaria diagnostics using three-dimensional printing

TitleRapid prototyping aptamer-enabled malaria diagnostics using three-dimensional printing
Authors
Liang, SDirkzwager, RMTanner, JA
Issue Date2016
Citation
The 3rd Oxford Symposium on Aptamers (Aptamers 2016), Oxford University, Oxford, UK., 4-5 April 2016. How to Cite?
AbstractThe integration of three-dimensional (3D) printing into diagnostic development gives the creative power for rapid prototyping diagnostic devices by adapting basic molecular technologies. Thanks to the quick printing time and low printing cost, customized parts can be generated to fit different assay formats and optimized via the process of “design – test – redesign”. In this study, we present the development of 3D printed aptamer-enabled diagnostic devices based on our previously reported aptamer-tethered enzyme capture (APTEC) assay for malaria diagnosis. A paper-based syringe test and a magnetic bead-based well test were developed using 3D printed parts. Both were found to successfully detect …
Persistent Identifierhttp://hdl.handle.net/10722/225598

 

DC FieldValueLanguage
dc.contributor.authorLiang, S-
dc.contributor.authorDirkzwager, RM-
dc.contributor.authorTanner, JA-
dc.date.accessioned2016-05-20T08:09:13Z-
dc.date.available2016-05-20T08:09:13Z-
dc.date.issued2016-
dc.identifier.citationThe 3rd Oxford Symposium on Aptamers (Aptamers 2016), Oxford University, Oxford, UK., 4-5 April 2016.-
dc.identifier.urihttp://hdl.handle.net/10722/225598-
dc.description.abstractThe integration of three-dimensional (3D) printing into diagnostic development gives the creative power for rapid prototyping diagnostic devices by adapting basic molecular technologies. Thanks to the quick printing time and low printing cost, customized parts can be generated to fit different assay formats and optimized via the process of “design – test – redesign”. In this study, we present the development of 3D printed aptamer-enabled diagnostic devices based on our previously reported aptamer-tethered enzyme capture (APTEC) assay for malaria diagnosis. A paper-based syringe test and a magnetic bead-based well test were developed using 3D printed parts. Both were found to successfully detect …-
dc.languageeng-
dc.relation.ispartofOxford Symposium on Aptamers, Aptamers 2016-
dc.titleRapid prototyping aptamer-enabled malaria diagnostics using three-dimensional printing-
dc.typeConference_Paper-
dc.identifier.emailTanner, JA: jatanner@hkucc.hku.hk-
dc.identifier.authorityTanner, JA=rp00495-
dc.identifier.hkuros257941-

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