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Article: Uncovering the Anticancer Mechanisms of Chinese Herbal Medicine Formulas: Therapeutic Alternatives for Liver Cancer

TitleUncovering the Anticancer Mechanisms of Chinese Herbal Medicine Formulas: Therapeutic Alternatives for Liver Cancer
Authors
CHEN, FZhong, ZTan, HYGUO, WZHANG, CTAM, C-WLi, SWang, NFeng, Y
Keywordscancer
liver cancer
hepatocellular carcinoma
Chinese herbal medicine formula
alternative therapy
Issue Date2020
PublisherFrontiers Research Foundation. The Journal's web site is located at http://www.frontiersin.org/pharmacology
Citation
Frontiers in Pharmacology, 2020, v. 11, p. article no. 293 How to Cite?
DOI: http://dx.doi.org/10.3389/fphar.2020.00293
AbstractThe potential values of Chinese herbal formulas in treating various diseases are well known. In addition to more than 2,000 years of history, herbal medicine is appreciated for its remarkable efficacy in a lot of cases, which warrants a role in public health care worldwide, especially in East Asian countries. Liver cancer is the second most fatal cancer across the world. Recent studies have extensively investigated the chemical profiles and pharmacological effects of Chinese herbal medicine formulas on liver cancer. Either through observational follow-up or experimental studies, multiple herbal formulas have benefits implicated in the management of liver cancer. However, complex composition of each formula imposes restrictions on promoting clinical practice and global recognition. Therefore, understanding the mode of action of Chinese herbal medicine formulas in depth may offer sufficient evidence for their clinical use. This review highlighted the chemical characteristics and molecular mechanisms of actions of prominent Chinese herbal medicine formulas and summarized the correlated findings on the potential use in liver cancer treatment. At last, the present progresses of Chinese herbal medicine formulas in the perspective of clinical trials are discussed.
Persistent Identifierhttp://hdl.handle.net/10722/282254
ISSN
1663-9812
2021 Impact Factor: 5.988
2020 SCImago Journal Rankings: 1.384
ISI Accession Number ID
WOS:000525610400001

 

DC FieldValueLanguage
dc.contributor.authorCHEN, F-
dc.contributor.authorZhong, Z-
dc.contributor.authorTan, HY-
dc.contributor.authorGUO, W-
dc.contributor.authorZHANG, C-
dc.contributor.authorTAM, C-W-
dc.contributor.authorLi, S-
dc.contributor.authorWang, N-
dc.contributor.authorFeng, Y-
dc.date.accessioned2020-05-05T14:32:46Z-
dc.date.available2020-05-05T14:32:46Z-
dc.date.issued2020-
dc.identifier.citationFrontiers in Pharmacology, 2020, v. 11, p. article no. 293-
dc.identifier.issn1663-9812-
dc.identifier.urihttp://hdl.handle.net/10722/282254-
dc.description.abstractThe potential values of Chinese herbal formulas in treating various diseases are well known. In addition to more than 2,000 years of history, herbal medicine is appreciated for its remarkable efficacy in a lot of cases, which warrants a role in public health care worldwide, especially in East Asian countries. Liver cancer is the second most fatal cancer across the world. Recent studies have extensively investigated the chemical profiles and pharmacological effects of Chinese herbal medicine formulas on liver cancer. Either through observational follow-up or experimental studies, multiple herbal formulas have benefits implicated in the management of liver cancer. However, complex composition of each formula imposes restrictions on promoting clinical practice and global recognition. Therefore, understanding the mode of action of Chinese herbal medicine formulas in depth may offer sufficient evidence for their clinical use. This review highlighted the chemical characteristics and molecular mechanisms of actions of prominent Chinese herbal medicine formulas and summarized the correlated findings on the potential use in liver cancer treatment. At last, the present progresses of Chinese herbal medicine formulas in the perspective of clinical trials are discussed.-
dc.languageeng-
dc.publisherFrontiers Research Foundation. The Journal's web site is located at http://www.frontiersin.org/pharmacology-
dc.relation.ispartofFrontiers in Pharmacology-
dc.rightsThis Document is Protected by copyright and was first published by Frontiers. All rights reserved. It is reproduced with permission.-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectcancer-
dc.subjectliver cancer-
dc.subjecthepatocellular carcinoma-
dc.subjectChinese herbal medicine formula-
dc.subjectalternative therapy-
dc.titleUncovering the Anticancer Mechanisms of Chinese Herbal Medicine Formulas: Therapeutic Alternatives for Liver Cancer-
dc.typeArticle-
dc.identifier.emailZhong, Z: zfzhong@hku.hk-
dc.identifier.emailTan, HY: hyhtan@hku.hk-
dc.identifier.emailLi, S: lishaha@hku.hk-
dc.identifier.emailWang, N: ckwang@hku.hk-
dc.identifier.emailFeng, Y: yfeng@hku.hk-
dc.identifier.authorityWang, N=rp02075-
dc.identifier.authorityFeng, Y=rp00466-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3389/fphar.2020.00293-
dc.identifier.scopuseid_2-s2.0-85082689196-
dc.identifier.hkuros309772-
dc.identifier.volume11-
dc.identifier.spagearticle no. 293-
dc.identifier.epagearticle no. 293-
dc.identifier.isiWOS:000525610400001-
dc.publisher.placeSwitzerland-
dc.identifier.issnl1663-9812-

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