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Conference Paper: Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src activation

TitleDownregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src activation
Authors
Mak, VCYLee, LSiu, MKYWong, OGWLu, XNgan, HYSWong, ESYCheung, ANY
Issue Date2011
PublisherAmerican Association for Cancer Research.
Citation
The 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. How to Cite?
AbstractGestational choriocarcinoma is a malignant tumour derived from placental trophoblast and is the most aggressive member of gestational trophoblastic disease (GTD). Apoptotic stimulating protein of p53-2 (ASPP2) is a tumor suppressor member of the ASPP family which transactivates p53-dependent apoptotic pathway. In this study, we examined the expression profile of ASPP2 in choriocarcinoma in comparison with normal placentas and hydatidiform moles which is a type of GTD that carries malignant potential. Results from quantitative PCR and immunohistochemical studies showed that downregulation of ASPP2 was detected in ...
DescriptionPoster Session 7 - Signaling Pathways Involved in Oncogenesis and Tumor Suppression: abstract no. 2107
Persistent Identifierhttp://hdl.handle.net/10722/169374

 

DC FieldValueLanguage
dc.contributor.authorMak, VCYen_US
dc.contributor.authorLee, Len_US
dc.contributor.authorSiu, MKYen_US
dc.contributor.authorWong, OGWen_US
dc.contributor.authorLu, Xen_US
dc.contributor.authorNgan, HYSen_US
dc.contributor.authorWong, ESYen_US
dc.contributor.authorCheung, ANYen_US
dc.date.accessioned2012-10-18T08:52:10Z-
dc.date.available2012-10-18T08:52:10Z-
dc.date.issued2011en_US
dc.identifier.citationThe 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011.en_US
dc.identifier.urihttp://hdl.handle.net/10722/169374-
dc.descriptionPoster Session 7 - Signaling Pathways Involved in Oncogenesis and Tumor Suppression: abstract no. 2107-
dc.description.abstractGestational choriocarcinoma is a malignant tumour derived from placental trophoblast and is the most aggressive member of gestational trophoblastic disease (GTD). Apoptotic stimulating protein of p53-2 (ASPP2) is a tumor suppressor member of the ASPP family which transactivates p53-dependent apoptotic pathway. In this study, we examined the expression profile of ASPP2 in choriocarcinoma in comparison with normal placentas and hydatidiform moles which is a type of GTD that carries malignant potential. Results from quantitative PCR and immunohistochemical studies showed that downregulation of ASPP2 was detected in ...-
dc.languageengen_US
dc.publisherAmerican Association for Cancer Research.-
dc.relation.ispartofAnnual Meeting of the American Association for Cancer Research, AACR 2011en_US
dc.titleDownregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src activationen_US
dc.typeConference_Paperen_US
dc.identifier.emailMak, VCY: h0124398@graduate.hku.hken_US
dc.identifier.emailSiu, MKY: mkysiu@hku.hken_US
dc.identifier.emailWong, OGW: wonggw@hkucc.hku.hken_US
dc.identifier.emailNgan, HYS: hysngan@hkucc.hku.hken_US
dc.identifier.emailWong, ESY: esywong@hkucc.hku.hken_US
dc.identifier.emailCheung, ANY: anycheun@hkucc.hku.hk-
dc.identifier.authoritySiu, MKY=rp00275en_US
dc.identifier.authorityNgan, HYS=rp00346en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros212024en_US
dc.publisher.placeUnited States-
dc.description.otherThe 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011.-

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