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Conference Paper: Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src activation
Title | Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src activation |
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Authors | |
Issue Date | 2011 |
Publisher | American Association for Cancer Research. |
Citation | The 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. How to Cite? |
Abstract | Gestational choriocarcinoma is a malignant tumour derived from placental trophoblast and is the most aggressive member of gestational trophoblastic disease (GTD). Apoptotic stimulating protein of p53-2 (ASPP2) is a tumor suppressor member of the ASPP family which transactivates p53-dependent apoptotic pathway. In this study, we examined the expression profile of ASPP2 in choriocarcinoma in comparison with normal placentas and hydatidiform moles which is a type of GTD that carries malignant potential. Results from quantitative PCR and immunohistochemical studies showed that downregulation of ASPP2 was detected in ... |
Description | Poster Session 7 - Signaling Pathways Involved in Oncogenesis and Tumor Suppression: abstract no. 2107 |
Persistent Identifier | http://hdl.handle.net/10722/169374 |
DC Field | Value | Language |
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dc.contributor.author | Mak, VCY | en_US |
dc.contributor.author | Lee, L | en_US |
dc.contributor.author | Siu, MKY | en_US |
dc.contributor.author | Wong, OGW | en_US |
dc.contributor.author | Lu, X | en_US |
dc.contributor.author | Ngan, HYS | en_US |
dc.contributor.author | Wong, ESY | en_US |
dc.contributor.author | Cheung, ANY | en_US |
dc.date.accessioned | 2012-10-18T08:52:10Z | - |
dc.date.available | 2012-10-18T08:52:10Z | - |
dc.date.issued | 2011 | en_US |
dc.identifier.citation | The 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/169374 | - |
dc.description | Poster Session 7 - Signaling Pathways Involved in Oncogenesis and Tumor Suppression: abstract no. 2107 | - |
dc.description.abstract | Gestational choriocarcinoma is a malignant tumour derived from placental trophoblast and is the most aggressive member of gestational trophoblastic disease (GTD). Apoptotic stimulating protein of p53-2 (ASPP2) is a tumor suppressor member of the ASPP family which transactivates p53-dependent apoptotic pathway. In this study, we examined the expression profile of ASPP2 in choriocarcinoma in comparison with normal placentas and hydatidiform moles which is a type of GTD that carries malignant potential. Results from quantitative PCR and immunohistochemical studies showed that downregulation of ASPP2 was detected in ... | - |
dc.language | eng | en_US |
dc.publisher | American Association for Cancer Research. | - |
dc.relation.ispartof | Annual Meeting of the American Association for Cancer Research, AACR 2011 | en_US |
dc.title | Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src activation | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Mak, VCY: h0124398@graduate.hku.hk | en_US |
dc.identifier.email | Siu, MKY: mkysiu@hku.hk | en_US |
dc.identifier.email | Wong, OGW: wonggw@hkucc.hku.hk | en_US |
dc.identifier.email | Ngan, HYS: hysngan@hkucc.hku.hk | en_US |
dc.identifier.email | Wong, ESY: esywong@hkucc.hku.hk | en_US |
dc.identifier.email | Cheung, ANY: anycheun@hkucc.hku.hk | - |
dc.identifier.authority | Siu, MKY=rp00275 | en_US |
dc.identifier.authority | Ngan, HYS=rp00346 | en_US |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.hkuros | 212024 | en_US |
dc.publisher.place | United States | - |
dc.description.other | The 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. | - |