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Conference Paper: Dysregulated FBI-1 in gestational trophoblastic neoplasms
| Title | Dysregulated FBI-1 in gestational trophoblastic neoplasms |
|---|---|
| Authors | |
| Issue Date | 2011 |
| Publisher | American Association for Cancer Research. |
| Citation | The 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. How to Cite? |
| Abstract | BACKGROUND: Human placental trophoblast is considered as a pseudo-malignant tissue. Gestational trophoblastic disease (GTD) includes true malignancies such as choriocarcinomas and potentially malignant hydatidiform moles, which may develop into persistent gestational trophoblastic neoplasms requiring chemotherapy. FBI-1 (also called Pokemon/ZBTB7A) is a BTB/POZ-domain Krüppel-like zinc-finger transcription factor which can inactivate p53 through the ARF-MDM2-p53 pathway. This study investigated the expression and functional effects of FBI-1 in choriocarcinomas as compared with ... |
| Description | Poster Session 8 - p53 and Apoptosis Regulation: abstract no. 191 |
| Persistent Identifier | http://hdl.handle.net/10722/169375 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Mak, VCY | en_US |
| dc.contributor.author | Ng, WY | en_US |
| dc.contributor.author | Jiang, LL | en_US |
| dc.contributor.author | Siu, MKY | en_US |
| dc.contributor.author | Wong, OGW | en_US |
| dc.contributor.author | Ngan, HYS | en_US |
| dc.contributor.author | Cheung, ANY | en_US |
| dc.date.accessioned | 2012-10-18T08:52:10Z | - |
| dc.date.available | 2012-10-18T08:52:10Z | - |
| dc.date.issued | 2011 | en_US |
| dc.identifier.citation | The 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. | en_US |
| dc.identifier.uri | http://hdl.handle.net/10722/169375 | - |
| dc.description | Poster Session 8 - p53 and Apoptosis Regulation: abstract no. 191 | - |
| dc.description.abstract | BACKGROUND: Human placental trophoblast is considered as a pseudo-malignant tissue. Gestational trophoblastic disease (GTD) includes true malignancies such as choriocarcinomas and potentially malignant hydatidiform moles, which may develop into persistent gestational trophoblastic neoplasms requiring chemotherapy. FBI-1 (also called Pokemon/ZBTB7A) is a BTB/POZ-domain Krüppel-like zinc-finger transcription factor which can inactivate p53 through the ARF-MDM2-p53 pathway. This study investigated the expression and functional effects of FBI-1 in choriocarcinomas as compared with ... | - |
| dc.language | eng | en_US |
| dc.publisher | American Association for Cancer Research. | - |
| dc.relation.ispartof | Annual Meeting of the American Association for Cancer Research, AACR 2011 | en_US |
| dc.title | Dysregulated FBI-1 in gestational trophoblastic neoplasms | en_US |
| dc.type | Conference_Paper | en_US |
| dc.identifier.email | Mak, VCY: h0124398@graduate.hku.hk | en_US |
| dc.identifier.email | Siu, MKY: mkysiu@hku.hk | en_US |
| dc.identifier.email | Wong, OGW: wonggw@hkucc.hku.hk | en_US |
| dc.identifier.email | Ngan, HYS: hysngan@hkucc.hku.hk | en_US |
| dc.identifier.email | Cheung, ANY: anycheun@hkucc.hku.hk | - |
| dc.identifier.authority | Siu, MKY=rp00275 | en_US |
| dc.identifier.authority | Ngan, HYS=rp00346 | en_US |
| dc.description.nature | link_to_OA_fulltext | - |
| dc.identifier.hkuros | 212025 | en_US |
| dc.publisher.place | United States | - |
| dc.description.other | The 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. | - |