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Conference Paper: Overexpression of Hexokinase 2 (HK2) in ovarian cancer contributes to cell migration, invasion and cancer stem-like cells regulation and correlates with poor patient survival

TitleOverexpression of Hexokinase 2 (HK2) in ovarian cancer contributes to cell migration, invasion and cancer stem-like cells regulation and correlates with poor patient survival
Authors
Siu, MKYJiang, YCheung, ANYNgan, HYSChan, KKL
Issue Date2015
PublisherEACR-AACR-SIC 2015. The Conference proceedings' website is located at http://www.ecco-org.eu/~/media/Documents/ECCO%20sections/Events/EAS2015/EAS2015%20Proceedings%20Book.pdf
Citation
The 2015 EACR-AACR-SIC Special Conference, Florence, Italy, 20-23 June 2015. In Conference Proceedings, 2015, p. 62, abstract no. 144 How to Cite?
AbstractINTRODUCTION: Altered glucose metabolism is a new hallmark for cancer. High lactate production and low glucose oxidation, regardless of the oxygen availability, known as the Warburg effect (aerobic glycolysis), are commonly found in cancers. Hexokinase 2 (HK2) converts glucose to glucose-6- phosphate, the first committed step in glycolysis. HK2 regulates glycolysis and tumorigenesis in different human cancers, yet the mechanisms remain poorly defined. In this study, we investigate the clinical significance, effects and mechanisms of HK2 on cell migration, invasion and cancer ...
DescriptionConference Theme: Anticancer Drug Action and Drug Resistance: From Cancer Biology to the Clinic
Poster Session - Carcinogenesis 1: abstract no. 144
Persistent Identifierhttp://hdl.handle.net/10722/213633

 

DC FieldValueLanguage
dc.contributor.authorSiu, MKY-
dc.contributor.authorJiang, Y-
dc.contributor.authorCheung, ANY-
dc.contributor.authorNgan, HYS-
dc.contributor.authorChan, KKL-
dc.date.accessioned2015-08-07T07:22:23Z-
dc.date.available2015-08-07T07:22:23Z-
dc.date.issued2015-
dc.identifier.citationThe 2015 EACR-AACR-SIC Special Conference, Florence, Italy, 20-23 June 2015. In Conference Proceedings, 2015, p. 62, abstract no. 144-
dc.identifier.urihttp://hdl.handle.net/10722/213633-
dc.descriptionConference Theme: Anticancer Drug Action and Drug Resistance: From Cancer Biology to the Clinic-
dc.descriptionPoster Session - Carcinogenesis 1: abstract no. 144-
dc.description.abstractINTRODUCTION: Altered glucose metabolism is a new hallmark for cancer. High lactate production and low glucose oxidation, regardless of the oxygen availability, known as the Warburg effect (aerobic glycolysis), are commonly found in cancers. Hexokinase 2 (HK2) converts glucose to glucose-6- phosphate, the first committed step in glycolysis. HK2 regulates glycolysis and tumorigenesis in different human cancers, yet the mechanisms remain poorly defined. In this study, we investigate the clinical significance, effects and mechanisms of HK2 on cell migration, invasion and cancer ...-
dc.languageeng-
dc.publisherEACR-AACR-SIC 2015. The Conference proceedings' website is located at http://www.ecco-org.eu/~/media/Documents/ECCO%20sections/Events/EAS2015/EAS2015%20Proceedings%20Book.pdf-
dc.relation.ispartofEACR-AACR-SIC 2015 Special Conference-
dc.titleOverexpression of Hexokinase 2 (HK2) in ovarian cancer contributes to cell migration, invasion and cancer stem-like cells regulation and correlates with poor patient survival-
dc.typeConference_Paper-
dc.identifier.emailSiu, MKY: mkysiu@hkucc.hku.hk-
dc.identifier.emailCheung, ANY: anycheun@hkucc.hku.hk-
dc.identifier.emailNgan, HYS: hysngan@hkucc.hku.hk-
dc.identifier.emailChan, KKL: kklchan@hkucc.hku.hk-
dc.identifier.authoritySiu, MKY=rp00275-
dc.identifier.authorityCheung, ANY=rp00542-
dc.identifier.authorityNgan, HYS=rp00346-
dc.identifier.authorityChan, KKL=rp00499-
dc.description.naturepostprint-
dc.identifier.hkuros247724-
dc.identifier.spage62, abstract no. 144-
dc.identifier.epage62, abstract no. 144-
dc.publisher.placeItaly-

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