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Title	Author(s)	Issue Date	Views
A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening Journal:Cell Stem Cell	Yan, HHN Siu, HC Law, SYK Ho, RSL Yue, SKS Tsui, WY Chan, D Chan, AS Ma, SKY Lam, KO Bartfeld, S Man, HY Lee, CH Chan, ASY Wong, WHJ Cheng, SWP Chan, KW Zhang, J Shi, J Fan, X Kwong, DLW Mak, TW Yuen, ST Clevers, H Leung, SY	2018	356
Altered regulation of DNA ligase IV activity by aberrant promoter DNA methylation and gene amplification in colorectal cancer Journal:Human Molecular Genetics	Kuhmann, C Li, C Kloor, M Salou, M Weigel, C Schmidt, CR Ng, WCL Tsui, WY Leung, SY Yuen, ST Becker, N Weichenhan, D Plass, C Schmezer, P Chan, TL Popanda, O	2014	83
Down-regulation of ID4 by promoter hypermethylation in gastric adenocarcinoma Proceeding/Conference:Annual Meeting of the Hong Kong Society of Gastroenterology, HKSGE 2003	Chan, ASW Tsui, WY Chen, X Chu, KM Chan, TL Chan, ASY Li, R So, S Yuen, ST Leung, SY	2003	128
Down-regulation of ID4 by promoter hypermethylation in gastric adenocarcinoma Proceeding/Conference:Analytical Cellular Pathology	Chan, ASW Tsui, WY Chen, X Chu, KM Chan, CTL Chan, ASY Li, R So, S Yuen, ST Leung, SY	2003	162
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma Journal:Oncogene	Chan, ASW Tsui, WY Chen, X Chu, KM Chan, TL Chan, ASY Li, R So, S Yuen, ST Leung, SY	2003	207
Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models Journal:Gut	Tong, Y Cheng, SWP OR, CS YUE, SK Siu, HC Ho, SLR Law, SYK Tsui, WY Chan, D Ma, SKY Lee, SP Chan, ASY Chan, AS Yun, SW Hui, HSE Yuen, ST Leung, SY Yan, HHN	2022	36
Establishment of a large-scale drug sensitivity screening platform on gastric cancer organoid cultures with potential to guide treatment Proceeding/Conference:American Association for Cancer Research (AACR) and Korean Cancer Association (KCA) Joint Conference on Precision Medicine in Solid Tumors	Yan, HHN Chan, D Siu, HC Law, SYK Ho, RSL Tsui, WY Yue, SKS Chan, AS Lee, CH Chan, ASY Chan, KW Leung, HC Hui, HS Lam, KO Kwong, DLW Mak, TW Clevers, H Leung, SY	2018	193
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer Proceeding/Conference:AACR Special Conference on Translation of the Cancer Genome: Scientific, Clinical, & Operational Challenges	Wang, K Tsui, WY Lee, SP Ho, RSL Chan, AKW Cheng, GHW Roberts, PC Rejto, PA Gibson, NW Kan, J Pocalyko, DJ Mao, M Xu, J Leung, SY Yuen, ST Shi, ST Chu, KM Law, SYK Chan, TL Kan, Z Chan, ASY	2011	62
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer Journal:Nature Genetics	Wang, K Kan, J Yuen, ST Shi, ST Chu, KM Law, S Chan, TL Kan, Z Chan, ASY Tsui, WY Lee, SP Ho, SL Chan, AKW Cheng, GHW Roberts, PC Rejto, PA Gibson, NW Pocalyko, DJ Mao, M Xu, J Leung, SY	2011	257
Expression of wnt signaling target genes in colorectal cancer progression Proceeding/Conference:Cancer Research	Guo, D Yuen, ST Tsui, WY Chan, ASY Chan, TL Leung, SY	2007	121
Frequent Inactivation of Axon Guidance Molecule RGMA in Human Colon Cancer Through Genetic and Epigenetic Mechanisms Journal:Gastroenterology	Li, VSW Yuen, ST Chan, TL Yan, HHN Law, WL Yeung, BHY Chan, ASY Tsui, WY So, S Chen, X Leung, SY	2009	190
Gastric cancer organoid culture shows preserved genomic stability in long-term passage Proceeding/Conference:Cancer Research	Yue, SK Yan, HHN Siu, HC Ho, RSL Tsui, WY Chan, D Chan, ASY Lee, CH Chan, AKW Leung, SY	2017	109
Gene expression profiling of human colon top versus basal crypts and identification of BMP antagonists as candidates for intestinal stem cell niche Proceeding/Conference:Keystone Symposium on Frontiers in Gastrointestinal Cancer: Molecular Genetics, Inflammation, Early Detection & Therapy	Li, VSW Kosinski, C Chan, ASY Zhang, J Ho, C Tsui, WY Chan, TL Mifflin, RC Powell, DW Yuen, ST Leung, SY Chen, X	2007	101
Germline epimutation of MLH1 in early-onset colorectal cancer Proceeding/Conference:Cancer Research	Chan, TL Tsui, WY Chan, YW Chan, ASY Lee, TYH Yuen, ST Leung, SY	2008	142
Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer Journal:Nature Genetics	Chan, TL Yuen, ST Kong, CK Chan, YW Chan, ASY Ng, WF Tsui, WY Lo, MWS Tam, WY Li, VSW Leung, SY	2006	138
Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1 Journal:Nature Genetics	Ligtenberg, MJL Kuiper, RP Chan, TL Goossens, M Hebeda, KM Voorendt, M Lee, TYH Bodmer, D Hoenselaar, E HendriksCornelissen, SJB Tsui, WY Kong, CK Brunner, HG Van Kessel, AG Yuen, ST Van Krieken, JHJM Leung, SY Hoogerbrugge, N	2009	198
Investigation of signaling pathways that regulate human colon crypt maturation and their dysregulation in tumorigenesis Proceeding/Conference:Cancer Research	Li, VSW Yuen, ST Chan, ASY Tsui, WY Chen, X Leung, SY	2007	120
Mutation of BRAF and KRAS in gastric cancer and their association with microsatellite instability Proceeding/Conference:Proceedings of the American Association for Cancer Research	Zhao, W Chan, TL Chu, KM Tsui, WY Chan, ASY Stratton, MR Yuen, ST Leung, SY	2003	131
Mutational landscape of normal epithelial cells in Lynch Syndrome patients Journal:Nature Communications	Lee, CH Robinson, PS Coorens, THH Yan, HHN Olafsson, S Lee-Six, H Sanders, MA Siu, HC Hewinson, J Yue, SKS Tsui, WY Chan, ASY Chan, KW Ho, SLR Campbell, PJ Martincorena, I Buczacki, SJA Yuen, ST Leung, SY Stratton, MR	2022	7
Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles Journal:Gut	Yan, HHN Siu, HC Ho, SL Yue, SKS Gao, Y Tsui, WY Chan, D Chan, AS Wong, JWH Man, AHY Lee, BCH Chan, ASY Chan, AKW Hui, HS Cheung, AKL Law, WL Lo, OSH Yuen, ST Clevers, H Leung, SY	2020	206

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